Flow in vitreous chamber under vitrectomy and its mechanical effect on retina

• Project/Area Number: 25289026
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Fluid engineering
• Research Institution: Meiji University
• Principal Investigator: Sakakibara Jun 明治大学, 理工学部, 准教授 (10292533)
• Co-Investigator(Kenkyū-buntansha): 加治 優一 筑波大学, 医学医療系, 准教授 (50361332) ; 大鹿 哲郎 筑波大学, 医学医療系, 教授 (90194133)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000); Fiscal Year 2016: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000); Fiscal Year 2013: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
• Keywords: 硝子体手術 / 生体内流動 / せん断応力 / 眼科学 / 画像計測 / PIV / スロッシング / 壁面せん断応力 / 気液二相流 / 三次元PTV / 流体工学 / 眼内流動 / ガスタンポナーデ / 眼科 / 網膜 / 乱流 / 球殻内流れ / 噴流 / 自励振動

Outline of Final Research Achievements

Velocity distribution and wall shear stress in the vitreous chamber during vitrectomy and after gas tamponade has been measured by use of eye model 4 times larger in its dimension. The maximum shear stress was 48Pa at 25G and 59Pa at 20G irrigation port during vitrectomy, and 12Pa after gas tamponade where linear acceleration was applied to the model partially filled with water. These shear stress were comparable to retinal adhesive strength such as 4~266Pa.

Research Products

• [Presentation] 硝子体手術後の頭部運動に起因する眼球内水流動 (2016)
  • Author(s): 五十嵐 和貴、吉田 拓真、河野 大樹、榊原 潤
  • Organizer: 第44回可視化情報シンポジウム
  • Place of Presentation: 工学院大学、新宿
  • Year and Date: 2016-07-19
• [Presentation] Visualization of Flow in Eye (2016)
  • Author(s): Jun Sakakibara
  • Organizer: 17th International Symposium on Flow Visualization
  • Place of Presentation: Tennessee, USA
  • Year and Date: 2016-06-19
  • Int'l Joint Research / Invited
• [Presentation] Flow inside an eye under vitreous surgery (2014)
  • Author(s): DAIKI KONO, SHUN SAKAMOTO, JUN SAKAKIBARA
  • Organizer: 67th Annual Meeting of the American Physical Society Division of Fluid Dynamics
  • Place of Presentation: San Francisco, USA
  • Year and Date: 2014-11-23 – 2014-11-25
• [Presentation] 硝子体手術下における眼球内水流動 (2014)
  • Author(s): 河野 大樹，依田悠太郎，坂本 舜，榊原 潤
  • Organizer: 日本機械学会2014年度年次大会
  • Place of Presentation: 東京
  • Year and Date: 2014-09-07 – 2014-09-10
• [Presentation] 硝子体手術下における眼球内流速分布の測定 (2014)
  • Author(s): 依田悠太郎、榊原 潤
  • Organizer: 日本設計工学会 平成26年度 春季研究発表講演会
  • Place of Presentation: 明治大学（中野）