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Eating timing is a key regulator of matabolism

Research Project

Project/Area Number 25292069
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Food science
Research InstitutionNagoya University

Principal Investigator

Oda Hiroaki  名古屋大学, 生命農学研究科, 准教授 (20204208)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Keywords時間栄養学 / 概日時計 / メタボリックシンドローム / 肝臓時計 / メタボリック・シンドローム / 時計遺伝子
Outline of Final Research Achievements

Regular eating is good for your health. In our study, in order to clarify that eating timing is a key regulator of the metabolism, the following experiment was conducted. In three-dimensional primary cultured rat hepatocytes, microtubules played an important role in the circadian clock oscillation of hepatocytes. Eating rhythm disrupted rats fed a high cholesterol diet were used to see effects on serum cholesterol metabolism. Midnight snack syndrome model and rat model fed night and day every week repeatedly showed hypercholesterolemia.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • Research Products

    (14 results)

All 2015 2014 2013

All Journal Article (6 results) (of which Peer Reviewed: 1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 5 results)

  • [Journal Article] Chrononutrition2015

    • Author(s)
      Hiroaki Oda
    • Journal Title

      J. Nutr. Sci. Vitaminol.

      Volume: 61

    • NAID

      130005109869

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 時計遺伝子とメタボリック・シンドローム2014

    • Author(s)
      小田裕昭
    • Journal Title

      薬剤師会雑誌

      Volume: 66 Pages: 567-571

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 時計遺伝子と食事のリズム -メタボリックシンドロームにならないために-2014

    • Author(s)
      小田裕昭
    • Journal Title

      大阪市役所医師会報

      Volume: 130 Pages: 12-15

    • Related Report
      2014 Annual Research Report
  • [Journal Article] がんとアミノ酸代謝2014

    • Author(s)
      小田裕昭
    • Journal Title

      生化学

      Volume: 86 Pages: 332-337

    • Related Report
      2014 Annual Research Report
  • [Journal Article] 食事時間とメタボリックシンドローム2013

    • Author(s)
      小田裕昭
    • Journal Title

      日本医事新報.

      Volume: 4649 Pages: 86-87

    • Related Report
      2013 Annual Research Report
  • [Journal Article] 肝臓時計の新規同調因子として働くインスリンと生活習慣病予防 -腹時計の大切な働き-2013

    • Author(s)
      小田裕昭
    • Journal Title

      化学と生物

      Volume: 51 Pages: 518-520

    • NAID

      10031190487

    • Related Report
      2013 Annual Research Report
  • [Presentation] 時計遺伝子と疾患2015

    • Author(s)
      小田裕昭
    • Organizer
      第27回東海心臓リハビリテーション研究会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-25
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 必須アミノ酸の起源 ―栄養素の進化とアミノ酸必須性の起源―2015

    • Author(s)
      小田裕昭
    • Organizer
      第20回アミノ酸セミナー
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-27
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] SmartNutriStyle (Eating 5W1H): How regular eating timing regulates liver clock and metabolism2015

    • Author(s)
      Hiroaki Oda
    • Organizer
      Asian Congress of Nutrition 2015
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      2015-05-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 食スタイル(食の5W1H)の時間栄養学:食はどこに効くのか2015

    • Author(s)
      小田裕昭
    • Organizer
      時間栄養科学研究会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2015-02-14
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 摂食タイミング異常による肝臓概日時計の異常と脂質代謝異常2014

    • Author(s)
      小田裕昭、片岡裕太郎、小林悟、望月聡
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-11-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 摂食タイミングが体内時計を制御する分子メカニズム2014

    • Author(s)
      小田裕昭
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      酪農学園大学
    • Year and Date
      2014-06-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 摂食タイミング異常による肝臓時計異常と脂質代謝異常2014

    • Author(s)
      小田裕昭、片岡裕太郎、小林悟、望月聡
    • Organizer
      日本農芸化学会
    • Place of Presentation
      明治大学
    • Related Report
      2013 Annual Research Report
  • [Presentation] Chrono-nutrition: Molecular mechanism of disruption of liver clock by irregular feeding2013

    • Author(s)
      Oda H, Kataoka Y, Kobayashi S, Yamajuku D
    • Organizer
      20th International Congress Nutrition
    • Place of Presentation
      Granada, Spain
    • Related Report
      2013 Annual Research Report

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Published: 2013-05-21   Modified: 2019-07-29  

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