Development of Chemically Defined Culture Substrate for Cell Proliferation and Differentiation
| Project/Area Number |
25293403
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Partial Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | Hiroshima University |
|---|
Principal Investigator |
Hirata Isao 広島大学, 医歯薬保健学研究院(歯), 助教 (40346507)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KANAWA Masami 広島大学, 自然科学研究支援開発センター, 助教 (00284208)
KATO Koichi 広島大学, 大学院医歯薬保健学研究院(歯), 教授 (50283875)
KATO Yukio 広島大学, 大学院医歯薬保健学研究院(歯), 研究員 (10112062)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
|
|---|
| Keywords | 再生医学 / 表面・界面物性 / 細胞・組織 / ナノ薄膜 / 表面･界面物性 / 細胞･組織 / 間葉系幹細胞 / 幹葉系幹細胞 |
|---|
| Outline of Final Research Achievements |
A study of cell culture substrates requires the technology of the surface physical chemistry in addition to biology, so these progresses are slow. However this research is very important because the scaffold on which cells to live. This study was aimed precise control of proliferation and differentiation of cells, we developed a chemically defined culture substrate whose surface precisely controlled in nano-order. In particular cause of improvement of proliferation of mesenchymal stem cells on well-defined substrate, it has been suggested to be due to the maintenance of stemness.
|
Report
(4 results)
Research Products
(7 results)
