| Project/Area Number |
25293450
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Clinical nursing
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| Research Institution | National Center for Global Health and Medicine |
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Principal Investigator |
TONOSAKI AKIKO 国立研究開発法人国立国際医療研究センター, 国立看護大学校, 教授 (20317621)
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| Co-Investigator(Kenkyū-buntansha) |
松澤 智史 東京理科大学, 理工学部, 助教 (20385529)
田畑 耕治 東京理科大学, 理工学部, 講師 (30453814)
浅野 真誠 徳山工業高等専門学校, その他部局等, 准教授 (80408707)
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| Research Collaborator |
TAKEDA YUUICHIROU 国立研究開発法人国立国際医療研究センター, 国立国際医療研究センター病院・第3呼吸器内科, 医長 (70727156)
HASHIMOTO MASANORI 国立研究開発法人国立国際医療研究センター, 国立国際医療研究センター病院, 外科医長 (20251209)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
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| Keywords | 癌化学療法 / 通信システム / 有害事象 / 発症予測 / 身体活動量 / セルフケア / セルフモニタリング / 有害事象発症予測 / 発熱性好中球減少症 / 症状マネジメント / 発症予測式 / 情報通信システム / 癌 / 化学療法 / 身体組成 / 筋力 |
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| Outline of Final Research Achievements |
Patients with reduced muscle mass and depressive symptoms undergoing cancer chemotherapy also tend to have a low level of physical activity. Predicting the occurrence of febrile neutropenia (FN) in patients receiving chemotherapy is important for maintaining adequate levels of physical activity and quality of life. In the present study, we identified risk factors for FN by investigating the medical histories of patients with lung, breast, or colorectal cancer undergoing chemotherapy. Next, we developed a system in which patients undergoing chemotherapy at home would self-monitor their body temperature, fatigue level, and other physical characteristics using a tablet computer. Next, they sent the data, and if the risk of FN had increased, an alert was generated. Significant increases were seen in the risk of FN among patients with a history of sepsis from chemotherapy or of granulocyte colony stimulating factor therapy.
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