The pathology of hypotonia and postural disorder on abdominal muscles related to cerebral diseases
| Project/Area Number |
25350621
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kyorin University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
佐々木 誠一 茨城県立医療大学, 保健医療学部, 教授 (50153987)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 脳障害 / 姿勢障害 / 腹壁筋 |
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| Outline of Final Research Achievements |
In order to clarify the pathology such as hypotonic state and postural disorder of the abdominal muscles seen after brain injury, the mechanism of motor control was investigated. First, intracellular recordings were taken from abdominal muscle motoneurons and the properties of the spinal reflex mechanism were analyzed electrophysiologically. As a result, monosynaptic excitatory postsynaptic potentials were observed only in the Ia group afferent fiber stimulation derived from the homologous muscle. Furthermore, the vestibular inpust to the abdominal muscle motoneurons were analyzed. As a result, excitatory postsynaptic potentials were observed from about 20% of the motoneurons on the ipsilateral and contralateral side to the stimulations of the vestibular nucleus. It was suggested that the abdominal muscles have a unique spinal reflex mechanism and about 20% of the motoneurons received input from the vestibular nucleus.
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Report
(5 results)
Research Products
(2 results)
