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The pathology of hypotonia and postural disorder on abdominal muscles related to cerebral diseases

Research Project

Project/Area Number 25350621
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKyorin University

Principal Investigator

Niwa Masatoshi  杏林大学, 保健学部, 教授 (90274985)

Co-Investigator(Kenkyū-buntansha) 佐々木 誠一  茨城県立医療大学, 保健医療学部, 教授 (50153987)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords脳障害 / 姿勢障害 / 腹壁筋
Outline of Final Research Achievements

In order to clarify the pathology such as hypotonic state and postural disorder of the abdominal muscles seen after brain injury, the mechanism of motor control was investigated. First, intracellular recordings were taken from abdominal muscle motoneurons and the properties of the spinal reflex mechanism were analyzed electrophysiologically. As a result, monosynaptic excitatory postsynaptic potentials were observed only in the Ia group afferent fiber stimulation derived from the homologous muscle. Furthermore, the vestibular inpust to the abdominal muscle motoneurons were analyzed. As a result, excitatory postsynaptic potentials were observed from about 20% of the motoneurons on the ipsilateral and contralateral side to the stimulations of the vestibular nucleus. It was suggested that the abdominal muscles have a unique spinal reflex mechanism and about 20% of the motoneurons received input from the vestibular nucleus.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2015 2014

All Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] The property of Ia excitation and recurrent inhibition of abdominal motoneurons in the cat.2015

    • Author(s)
      Masatoshi Niwa, Sei-Ichi Sasaki
    • Organizer
      Society for Neuroscience Annual Meeting
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2015-10-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] The property of Ia excitation and recurrent inhibition of abdominal motoneurons in the cat2014

    • Author(s)
      丹羽正利、佐々木誠一
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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