Understanding the molecular mechanism underlying immune response via perception of viral pathogen-associated molecular pattern in plant
| Project/Area Number |
25450055
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plant protection science
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| Research Institution | Hokkaido University |
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Principal Investigator |
NAKAHARA Kenji 北海道大学, (連合)農学研究科(研究院), 講師 (90315606)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 免疫受容体 / カルモジュリン様タンパク質 / RNAサイレンシング / 全身獲得抵抗性 / サリチル酸シグナリング / 植物ウイルス / RNAサイレンシング抑制タンパク質 / プライミング / ウイルス / 植物 / オートファジー / rgs-CaM / CML / サリチル酸シグナル / 自然免疫 / カルモジュリン / PAMPs |
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| Outline of Final Research Achievements |
Tobacco calmodulin-like protein rss-CaM is shown to be an immune receptor to induce salicylic acid signaling via perception of viral RNA silencing suppressor and calcium influx as virus infection cues. We have previously revealed that rgs-CaM enforces antiviral RNA silencing by binding to and directing degradation of RNA silencing suppressors via autophagy. Here, we show the activation of this antiviral function of rgs-CaM by salicylic acid signaling. Our results suggest that these rgs-CaM functions contribute to systemic acquired resistance against virus.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Truncated yet functional viral protein produced via RNA polymerase slippage implies underestimated coding capacity of RNA viruses2016
Author(s)
Yuka Hagiwara-Komoda, Sun Hee Choi2, Masanao Sato, Go Atsumi, Junya Abe, Junya Fukuda, Mie N. Honjo, Atsushi J. Nagano, Keisuke Komoda, Kenji S. Nakahara, Ichiro Uyeda, Satoshi Naito
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Journal Title
Scientific Reports
Volume: 6
Issue: 1
Pages: 21411-21411
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] P3N-PIPO of Clover yellow vein virus exacerbates symptoms in pea infected with White clover mosaic virus and is implicated in viral synergism2014
Author(s)
Hisa, Y., Suzuki, H., Atsumi, G., Choi, S.H., Nakahara, K.S., Uyeda, I.
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Journal Title
Virology
Volume: 449
Pages: 200-206
DOI
Related Report
Peer Reviewed
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