| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
In the present study, we constructed the experimental model using the intracranial self-stimulation to evaluate "motivation" and assessed the impact of drug administration on the motivation. The intracranial self-stimulation behavior is one of the experimental method for the assessment of brain reward function.As a result, it was demonstrated that brain dopamine nerves showed an important role in motivation, and that amplifying the action of dopamine which was released from the nerve terminal would be important in improving motivation. In addition, it was suggested that the brain nerve cell was possibility activated by the acquisition of motivated behavior.
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