Research for analysis by the claster of amnion derived stem cell

• Project/Area Number: 25460264
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: General anatomy (including histology/embryology)
• Research Institution: University of Toyama
• Principal Investigator: Yoshida Toshiko 富山大学, 大学院医学薬学研究部(医学), 准教授 (00171421)
• Co-Investigator(Kenkyū-buntansha): NIKAIDO TOSHIO 富山大学, 事務局, 理事・副学長 (50180568) ; OKABE MOTONORI 富山大学, 大学院医学薬学研究部(医学), 助教 (60283066) ; KOIKE CHIKA 富山大学, 大学院医学薬学研究部(医学), 助教 (10523889)
• Co-Investigator(Renkei-kenkyūsha): SAITOU SHIGERU 富山大学, 大学院医学薬学研究部(医学), 教授 (30175351) ; FUKUOKA JOUNYA 長崎大学, 医学部医学科, 臨床病理教授 (00324575)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 羊膜幹細胞クラスター / 羊膜由来細胞 / 組織再構築 / 疾患モデル / 抗炎症効果 / 羊膜由来幹細胞 / 間葉系幹細胞HAMα / 神経再生 / 関節炎モデル / 治療的処置 / 羊膜間葉系細胞 / 肝硬変モデルマウス / 変形性関節炎モデルマウス / 多発性硬化症モデルマウス / コリントランスポーター遺伝子導入細胞 / 羊膜幹細胞クラスター移植 / 羊膜幹細胞 / 羊膜上皮細胞 / 幹細胞クラスター / 細胞表面マーカー / Tra-1-60 / 肝細胞 / 分化誘導

Outline of Final Research Achievements

Obstinacy, the stem cell cluster which is 4 kinds from an amnion for the purpose of developing treatment method to a disease, funshu, a way was established. The reorganization effect of the organization was considered by the way to transplant to a disease model in in vivo by the way by which cocultivate makes the different kind of stem cell cluster supplementation of organization in in vitro for the purpose of organization reorganization by control of the minute society.
You can supply the cell transplantation with which a different cluster was combined like 2 examples of above with the original organization and put environmental control of cell growing into effect at the same time, it's more efficient to save and a tissue reconstruction can be done naturally. Use of an amnion origin stem cell cluster is a significant one as one of effective treatment methods to a refractory disease.

Research Products

• [Journal Article] Construction and characterization of human oral mucosa equivalent using hyper-dry amniotic membrane as a matrix. (2016)
  • Author(s): Qi Fangfang, Toshiko Yoshida, Takeshi Koike, Hitoshi Aizawa, Tetsu Shimane, Yinghui Li, Shinichi Yamada, Motonori Okabe, Toshiko Nikaido, Hiroshi Kurita.
  • Journal Title: Archives of Oral Biology Volume: 65 Pages: 26-34
  • DOI: 10.1016/j.archoralbio.2016.01.011
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Bioprinting with pre-cultured cellular constructs towards tissue engineering of hierarchical tissues. (2015)
  • Author(s): Nakamura M, Mir T A, Arai K, Ito S, Yoshida T, Iwanaga S, Kitano H, Obara C, Nikaido T..
  • Journal Title: International Journal of Bioprinting Volume: 1(1) Issue: 1 Pages: 39-48
  • DOI: 10.18063/ijb.2015.01.007
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Use of hyperdry amniotic membrane in operations for cleft palate: a study in rats. (2015)
  • Author(s): Hiroaki Tsuno, Makoto Noguchia, Motonori Okabeb, Kei Tomiharaa, Toshiko Yoshidab,Toshio Nikaido.
  • Journal Title: British Journal of Oral and Maxillofacial Surgery Volume: 53(4) Pages: 358-63
  • Peer Reviewed / Open Access
• [Journal Article] Hyperdry human amniotic membrrane is useful material for tissue engineering:physical, morphological properties, and safety as the new biological material. (2014)
  • Author(s): 1) Okabe M, Kitagawa K, Yoshida T, Suzuki T, Waki H, Koike C, Furuichi E, Katou K, Nomura Y, Uji Y, Hayashi A, Saito S, Nikaido T.
  • Journal Title: J Biomed Mater Res A. Volume: 102 Issue: 11 Pages: 862-870
  • DOI: 10.1002/jbm.a.35486
  • Peer Reviewed / Open Access
• [Journal Article] Characterization of amniotic stem cells. (2014)
  • Author(s): 2) Koike C, Zhou K, Takeda Y, Fathy M, Okabe M, Yoshida T, Nakamura Y, Kato Y, Nikaido T.
  • Journal Title: Cellular Reprogramming. Volume: 16 Pages: 298-305
  • Peer Reviewed
• [Journal Article] Intraoral application of hyperdry amniotic membrane to surgically exposed bone surface. (2014)
  • Author(s): 3) Tsuno H, AraiN, Sakai C, Okabe M, Koike C, YoshidaT, Nikaido T, Noguchi M.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol. Volume: 117
  • Peer Reviewed
• [Journal Article] Therapeutic potential of amnion epithelial cells for diabetes. (2014)
  • Author(s): Koike C, Okabe M, Yoshida T, and Nikaido T.
  • Journal Title: Perinatal Stem Cells. Volume: 23 Pages: 253-257
  • Peer Reviewed
• [Journal Article] Characteristics of human amniotic membrane and Application to regenerative medicine. (2014)
  • Author(s): Nikaido T.
  • Journal Title: Placenta. Volume: 35
  • Peer Reviewed
• [Journal Article] 耳科手術におけるHyperdryヒト乾燥羊膜の使用経験. (2014)
  • Author(s): 6) 將積日出夫, 藤坂実千郎, 髙倉大匡, 坪田雅仁, 金沢祐治, 舘野宏彦, 岡部素典, 吉田淑子, 二階堂敏雄.
  • Journal Title: 耳鼻臨床. Volume: 107 Pages: 172-180
  • NAID: 130003395623
  • Peer Reviewed
• [Journal Article] Hyperdry human amniotic membrarne is useful material for tissue engineering, physical, morphological properties, and safety as the new biological material. (2014)
  • Author(s): Okabe M. kitagawa K. Yoshida T. Suzuki T. Waki H. Koike C. Furuichi E. Katou K. Nomura Y. Uji Y. Hayashi A. Saito S. Nikaido T.
  • Journal Title: J Biomed Mater Res A Volume: 102 Pages: 862-870
  • Peer Reviewed
• [Journal Article] Intraoral application of hyperdry amniotic membrane to surgically exposed bone surface. (2014)
  • Author(s): Tsuno H. Arai N. Sakai C. Okabe M. Koike C. Yoshida T. Nikaido T. Noguchi M.
  • Journal Title: Oral Surg Oral Med Oral Pathol Oral Radiol Volume: 117
  • Peer Reviewed
• [Journal Article] Establishment of immortalized human amniotic mesenchymal stem cells (2013)
  • Author(s): Teng, Z.,Yoshida, T.,Okabe, M.,Toda, A.,Higuchi, O.,Nogami, M.,Yoneda, N.,Zhou, K.,Kyo, S.,Kiyono, T.,Nikaido, T
  • Journal Title: Cell Transplant Volume: 22(2) Issue: 2 Pages: 267-78
  • DOI: 10.3727/096368912x655055
  • Peer Reviewed
• [Journal Article] Selective isolation of Nanog positive human amniotic mesenchymal cells and differentiation into cardiomyocytes. (2013)
  • Author(s): Otaka S, Nagura S, Koike C, Okabe M, Yoshida T, Fathy M, Yanagi K, Misaki T, and Nikaido T.
  • Journal Title: Cellular Reprogramming. Volume: 15 Issue: 1 Pages: 80-91
  • DOI: 10.1089/cell.2012.0028
  • Peer Reviewed
• [Journal Article] Impaired autophagy by soluble endoglin, under physiological hypoxia in early pregnant period, is involved in poor placentation in preeclampsia. (2013)
  • Author(s): Nakashima A, Yamanaka-Tatematsu M, Fujita N, Koizumi K, Shima T, Yoshida T, Nikaido T, Okamoto A, Yoshimori T, Saito S.
  • Journal Title: Autophagy Volume: 9 Issue: 3 Pages: 303-316
  • DOI: 10.4161/auto.22927
  • Peer Reviewed
• [Journal Article] Application of 2-octyl-cyanoacrylate for corneal perforation and glaucoma filtering bleb leak (2013)
  • Author(s): Okabe M., Kitagawa K., Yoshida T., Koike C.,Katsumto T., Fujihara E., Nikaido T
  • Journal Title: Clinical Ophthalmology Volume: 7 Pages: 649-653
  • DOI: 10.2147/opth.s43106
  • Peer Reviewed
• [Journal Article] CD44- and SSEA-4- positive cells in an oral cancer cell line HSC-4 possess cancer stem-like cell characteristics. (2013)
  • Author(s): Noto Z, Yoshida T, Okabe M, Koike C, Fathy M, Tsuno H, Tomihara K, Arai N, Noguchi M, Nikaido T.
  • Journal Title: Oral Oncolog. Volume: 49 Pages: 787-795
  • Peer Reviewed
• [Journal Article] Effect of Exogenous Oct4 Overexpression on Cardiomyocyte Differentiation of Human Amniotic Mesenchymal Cells. (2013)
  • Author(s): Nagura S, Otaka S, Koike C, Okabe M, Yoshida T, Fathy M, Fukahara K, Yoshimura N, Misaki T, and Nikaido T.
  • Journal Title: Cellular Reprogramming Volume: 15 Issue: 5 Pages: 471-480
  • DOI: 10.1089/cell.2013.0002
  • Peer Reviewed
• [Journal Article] Establishment and characterization of immortalized human amniotic epithelial cells (2012)
  • Author(s): Zhou, K.,Koike, C.,Yoshida, T.,Okabe, M.,Fathy, M.,Kyo, S.,Kiyono, T.,Saito, S.,Nikaido, T
  • Journal Title: Cellular reprogramming Volume: 15 Issue: 1 Pages: 2012-21
  • DOI: 10.1089/cell.2012.0021
  • Peer Reviewed
• [Presentation] Direct reprogramming of immortalized human amniotic epithelial (iHAE) cells towards insulin producing cells (2016)
  • Author(s): Md. Faruk Hasan, Toshiko Yoshida, Motonori Okabe, Kaixuan Zhou, Chika Soko and Toshio Nikaido
  • Organizer: 第15回日本再生医療学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2016-03-17
• [Presentation] Identification of Cancer stem cells/cancer initiating cells in Endometrial cells (2016)
  • Author(s): Yi Sun1 , Toshiko Yoshida 1, Motonori Okabe 1, Kaixuan Zhou, Fang Wang, Chika Soko, Meijie Sang1 , Sigeru Saito, and Toshio Nikaido
  • Organizer: 第15回日本再生医療学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2016-03-17
• [Presentation] 肝硬変に対するヒト羊膜間葉系幹細胞（ HAMα）移植による効果 ーマウス肝硬変モデルを用いて (2016)
  • Author(s): 吉田 淑子、岡部 素典、吉田 聡、周 凱旋、相古 千加、斎藤 滋、二階堂 敏雄
  • Organizer: 第15回日本再生医療学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2016-03-17
• [Presentation] ハイパードライヒト乾燥羊膜の芽胞菌に対する殺菌効果：抗生物質との比較 (2016)
  • Author(s): 岡部素典、吉田淑子、坂本純子、北島 勲、小池千加、齋藤 滋、二階堂敏雄
  • Organizer: 第15回日本再生医療学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2016-03-17
• [Presentation] Direct reprogramming of immortalized human amniotic epithelial (iHAE) cells towards insulin producing cells. (2015)
  • Author(s): 2) Md. Faruk Hasan, Toshiko Yoshida, Motonori Okabe, Kaixuan Zhou, Chika Soko and Toshio Nikaido.
  • Organizer: 平成27年度 富山大学若手研究者等の学術交流・発表会
  • Place of Presentation: 富山
  • Year and Date: 2015-09-08
• [Presentation] Identification of cancer stem cells/cancer initiating cells in endometrial cancer cells. (2015)
  • Author(s): 3) Yi Sun, Toshiko Yoshida, Motonori Okabe, Kaixuan Zhou, Fang Wang, Chika Soko, Sigeru Saito, and Toshio Nikaido.
  • Organizer: 平成27年度 富山大学若手研究者等の学術交流・発表会
  • Place of Presentation: 富山
  • Year and Date: 2015-09-08
• [Presentation] Cancer stem cells/cancer initiating cells in cervical cancer cells. (2015)
  • Author(s): 4) Meijie Sang, Toshiko Yoshida, Motonori Okabe, Chika Koike, Kaixuan Zhou, Yi Sun, Fang Wang, Toshio Nikaido.
  • Organizer: 平成27年度 富山大学若手研究者等の学術交流・発表会
  • Place of Presentation: 富山
  • Year and Date: 2015-09-08
• [Presentation] 乾燥羊膜と絹由来タンパクによる新規バイオデバイスの開発 (2015)
  • Author(s): 岡部素典、吉田 淑子、鈴木 拓馬、小池 千加、野村 義宏、齋藤 滋、二階堂 敏雄
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] Immunosuppressive activity of amnion-derived cells (2015)
  • Author(s): Jiali Li、Toshiko Yoshida、Chika Koike-Soko、Motonori Okabe、Jun Sugimoto、Toshio Nikaido
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] Direct Reprogramming of Immortalized Human Amniotic Epithelial Cells towards insulin producing cells (2015)
  • Author(s): Hasan Faruk、Toshiko Yoshida、Motonori Okabe、Kaixuan Zhou、Chika Soko、Toshio Nikaido
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] 肝細胞の極性を制御できる3次元デバイスの作製 (2015)
  • Author(s): 荒井 健一、吉田 淑子、岡部 素典、小池 千加、二階堂 敏雄、赤池 敏宏、中村 真人
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] Identification of Cancer stem cells/cancer initiating cells in Endometrial cells (2015)
  • Author(s): Yi Sun、Toshiko Yoshida、Motonori Okabe、Kaixuan Zhou、Fang Wang、Chika Koike-soko、Shigeru Saito、Toshio Nikaido
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] CHT遺伝指導ヒト羊膜細胞の特徴 (2015)
  • Author(s): 吉田 佳奈美、吉田 淑子、岡部 素典、周 凱旋、相古 千加、二階堂 敏雄
  • Organizer: 第14回日本再生医療学会総会
  • Place of Presentation: 横浜
  • Year and Date: 2015-03-19 – 2015-03-21
• [Presentation] 再生医療材料として有効な羊膜幹細胞 (2015)
  • Author(s): 吉田淑子
  • Organizer: メデイカルジャパン2015
  • Place of Presentation: 大阪
  • Year and Date: 2015-02-04 – 2015-02-06
• [Presentation] 再生医学と研究倫理について. (2014)
  • Author(s): 二階堂敏雄.
  • Organizer: 平成26年度富山県試験研究機関研究員交流集会
  • Place of Presentation: 富山.
  • Year and Date: 2014-12-30
  • Invited
• [Presentation] Characteristics of Human Amniotic Membrane and Application to Regenerative Medicine. (2014)
  • Author(s): Nikaido T.
  • Organizer: 浙江大学医学院附属第一医院
  • Place of Presentation: 杭州, 中国．
  • Year and Date: 2014-12-09
  • Invited
• [Presentation] ヒト卵巣癌由来CD24(+)SSEA4(+)細胞の特性. (2014)
  • Author(s): 吉田淑子, Wang Fang, Zhou Kaixuan, 古市恵津子, 岡部素典, 吉田佳奈美, 齋藤 滋, 二階堂敏雄.
  • Organizer: 日本解剖学会第74回中部支部学術集会
  • Place of Presentation: 金沢
  • Year and Date: 2014-10-11 – 2014-10-12
• [Presentation] 卵巣癌に存在するCD24(+)SSEA4(+)細胞の特性. (2014)
  • Author(s): 吉田淑子, 王 芳, 齋藤 滋, 二階堂敏雄.
  • Organizer: 第73回日本癌学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2014-09-25 – 2014-09-27
• [Presentation] ヒト羊膜の再生医療への応用. (2014)
  • Author(s): 二階堂敏雄.
  • Organizer: 第３回富山・バーゼル医薬品研究開発シンポジウム
  • Place of Presentation: 富山.
  • Year and Date: 2014-08-12
  • Invited
• [Presentation] 細胞の甦り－細胞や組織は再生可能か？ (2014)
  • Author(s): 二階堂敏雄.
  • Organizer: 富山大学しらゆり会総会
  • Place of Presentation: 富山.
  • Year and Date: 2014-08-01
  • Invited
• [Presentation] CD24+SSEA4+ovarian carcinoma cells exhibit self renewal ability and tumorigenicity. (2014)
  • Author(s): 王 芳*, 吉田淑子, 岡部素典, 小池千加, 齋藤 滋, 二階堂敏雄.
  • Organizer: 第35回日本炎症・再生医学会
  • Place of Presentation: 沖縄
  • Year and Date: 2014-07-01 – 2014-07-04
• [Presentation] 羊膜（プラセンタ）は生活習慣病,アンチエイジングに有効！ (2014)
  • Author(s): 吉田淑子
  • Organizer: 第14回日本抗加齢医学学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2014-06-06 – 2014-06-08
• [Presentation] 羊膜を利用した再生医療はここまで進んでいる. (2014)
  • Author(s): 岡部素典
  • Organizer: 第14回日本抗加齢医学学会総会
  • Place of Presentation: 大阪
  • Year and Date: 2014-06-06 – 2014-06-08
• [Presentation] Application of Amniotic Membrane / Amnion-Derived Cells for Regenerative Medicine. (2014)
  • Author(s): Nikaido T.
  • Organizer: 河北医科大学
  • Place of Presentation: 石家庄, 中国
  • Year and Date: 2014-06-05 – 2014-06-13
  • Invited
• [Presentation] Application of Amniotic Membrane / Amnion-Derived Cells for Regenerative Medicine. (2014)
  • Author(s): Nikaido T.
  • Organizer: 同済大学附属肺科医院
  • Place of Presentation: 上海, 中国．
  • Year and Date: 2014-06-05 – 2014-06-13
  • Invited
• [Presentation] ヒト羊膜間葉系細胞（HAMα）およびヒト臍帯静脈上皮細胞（HUVEC）移植後のマウス肝硬変モデル. (2014)
  • Author(s): 吉田 淑子、岡部 素典、王 芳、吉田 佳奈美、小池 千加、齋藤 滋、二階堂 敏雄：
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] ヒト乾燥羊膜を用いた再生医療材料の作製. (2014)
  • Author(s): 岡部 素典、北川 清隆、吉田 淑子、小池 千加、鈴木 拓馬、野村 義宏、林 篤志、齋藤 滋、二階堂 敏雄
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] 羊膜由来幹細胞単離マーカーの探索. (2014)
  • Author(s): 小池 千加、吉田 淑子、岡部 素典、二階堂 敏雄
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] CD24+SSEA4+human ovariancarcinoma cells possessed the nature of cancer stem cells. (2014)
  • Author(s): 王 芳、吉田 淑子、岡部 素典、小池 千加、齋藤 滋、二階堂 敏雄
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] Immunosuppressive activity of amnion-derived cells. (2014)
  • Author(s): 李 佳麗、小池 千加、杉本 潤、吉田 淑子、岡部 素典、二階堂 敏雄
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] Human amnion epithelial cells expansion in vitroin a feeder cell dependent manner. (2014)
  • Author(s): Meijie Sang, Chika Koike, Toshiko Yoshida, Motonori Okabe, Toshio Nikaido
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] 高親和性コリントランスポーター（CHT）遺伝子導入ヒト羊膜上皮細胞の性質. (2014)
  • Author(s): 平田 陽子、吉田 淑子、周 凱旋、岡部 素典、小池 千加、二階堂 敏雄
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] ヒアルロン酸４糖（HA4）は末梢神経の再生を促進する：フィルムモデル法による検証. (2014)
  • Author(s): 鳥越 甲順、吉田 淑子、吉田 一晴
  • Organizer: 第13回日本再生医療学会総会
  • Place of Presentation: 京都
• [Presentation] 羊膜上皮系幹細胞と羊膜間葉系細胞の生活習慣病に対する効果. (2014)
  • Author(s): 吉田 淑子、岡部 素典、Li Jiali、小池 千加、吉田 佳奈美、吉田 聡、齋藤 滋、二階堂敏雄
  • Organizer: 第119回日本解剖学会総会・全国学術集会
  • Place of Presentation: 栃木
• [Presentation] ヒト羊膜幹細胞―問題点と特質点― (2014)
  • Author(s): 岡部 素典、吉田 淑子、野上 真紀子、津野 宏彰、小池 千加、竹田 祐治、木村 友厚、野口 誠、齋藤 滋、二階堂 敏雄
  • Organizer: 第119回日本解剖学会総会・全国学術集会
  • Place of Presentation: 栃木
• [Presentation] Therapeutic potential of amnion-derived cells. (2013)
  • Author(s): Nikaido T. , Yoshida T., Okabe M., Koike C.
  • Organizer: Cell Symposia : Using Stem Cells to Model and Treat Human Disease
  • Place of Presentation: Los Angeles, USA.
  • Invited
• [Presentation] 羊膜由来細胞の免疫抑制効果． (2013)
  • Author(s): 小池千加, Li Juali, 杉本 潤, 吉田淑子, 岡部素典, 二階堂敏雄.
  • Organizer: 第34回日本炎症・再生医学会
  • Place of Presentation: 京都
• [Presentation] 子宮頸癌に存在するCD24(+)CD44(+)細胞の特性. (2013)
  • Author(s): 23) 吉田淑子, 齋藤 滋, 二階堂敏雄.
  • Organizer: 第72回日本癌学会学術総会
  • Place of Presentation: 横浜
• [Remarks] 『富山大学杉谷（医薬系）キャンパス研究活動一覧』『富山医科薬科大学研究活動一覧』
  • URL: http://www.sugitani.u-toyama.ac.jp/library/kenkyu/index.html
• [Remarks] 富山大学大学院医学薬学研究部（医学）再生医学講座
  • URL: http://www.med.u-toyama.ac.jp/saiseiigaku/index.html
• [Remarks] 再生医学講座
  • URL: http://www.med.u-toyama.ac.jp/saiseiigaku/index.html
• [Patent(Industrial Property Rights)] Dried Amnion and Method for Drying Treatment of Amnion. (2013)
  • Inventor(s): 二階堂敏雄、吉田淑子、岡部素典、戸田文香、北川清隆、荒川雅彦
  • Industrial Property Rights Holder: 二階堂敏雄、吉田淑子、岡部素典、戸田文香、北川清隆、荒川雅彦
  • Industrial Property Rights Type: 特許
  • Filing Date: 2013-08-18
  • Acquisition Date: 2015-01-15
  • Overseas
• [Patent(Industrial Property Rights)] MEDICAL SUBSTITUTE MEMBRANE, USE THEROF, AND METHOD FOR REPAIR OF MEMBRANE TISSUE IN LIVING BODY (2013)
  • Inventor(s): 二階堂敏雄,岡部素典,吉田淑子,遠藤俊郎,林央周,齋藤滋
  • Industrial Property Rights Holder: 二階堂敏雄,岡部素典,吉田淑子,遠藤俊郎,林央周,齋藤滋
  • Industrial Property Rights Type: 特許
  • Filing Date: 2013-04-01
  • Acquisition Date: 2013-04-09
  • Overseas
• [Patent(Industrial Property Rights)] バイオコンジュゲートデバイス (2013)
  • Inventor(s): 岡部素典,二階堂敏雄,吉田淑子,小池知加,霞田隆治,古米保
  • Industrial Property Rights Holder: 岡部素典,二階堂敏雄,吉田淑子,小池知加,霞田隆治,古米保
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2013-136802
  • Filing Date: 2013-06-28