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Postmortem bacteria analysis of deaths due to sepsis

Research Project

Project/Area Number 25460870
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Legal medicine
Research InstitutionKyushu University

Principal Investigator

IKEDA NORIAKI  九州大学, 医学(系)研究科(研究院), 教授 (60176097)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords敗血症 / 法医解剖 / 細菌感染 / 腸内細菌 / 死後変化 / 起炎菌
Outline of Final Research Achievements

We collected the swab of nose, pharinx and both lung, and then did the cultivation of bacteria. An aseptic collecting method of these samples was established . The histopathological examination of infeced lung for the purpose of distinction between beore and after death revealed that the infection of gram negative vacteria might effect the outbreak of sepsis. After that, we used the genetic analyzer for the analysis to bacterial DNA of blood, lung swab and feces of large intestine. This method using genetic analyzer is useful for the diagnosis of sepsis.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (12 results)

All 2016 2015 2014 2013

All Journal Article (10 results) (of which Peer Reviewed: 10 results,  Open Access: 6 results) Presentation (1 results) Book (1 results)

  • [Journal Article] Expression of mRNA in the frontal cortex and hypothalamus in a rat model of acute carbon dioxide poisoning2016

    • Author(s)
      Kazuo Sato, Akiko Tsuji, Yosuke Usumoto, Keiko Kudo, Takeshi Yokoyama and Noriaki Ikeda
    • Journal Title

      Legal Medicine

      Volume: 19 Pages: 101-106

    • DOI

      10.1016/j.legalmed.2015.07.014

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A statistical analysis of standard organ weights and their changes during post-mortem interval using forensic autopsy cases2015

    • Author(s)
      Yousuke Usumoto, Kazumitsu Omura, Kazuo Sato, Naomi Sameshima, Keiko Kudo, Akiko Tsuji and Noriaki Ikeda
    • Journal Title

      Acta Crim Japon

      Volume: 81 Pages: 51-56

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anomalous origin of the right coronary artery from the left coronary sinus with an intramural course: comparison between sudden-death and non-sudden-death cases.2015

    • Author(s)
      Hata Y, Kinoshita K, Kudo K, Ikeda N, Nishida N
    • Journal Title

      Cardiovasc Pathol.

      Volume: 24 Issue: 3 Pages: 154-159

    • DOI

      10.1016/j.carpath.2014.11.004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A fatal case of poisoning related to new cathinone designer drugs2015

    • Author(s)
      Keiko Kudo, Yosuke Usumoto、Ruri Kikura-Hanajiri, Naomi Sameshima Akiko Tsuji and Noriaki Ikeda
    • Journal Title

      Legal Medicine

      Volume: 17 Issue: 5 Pages: 421-426

    • DOI

      10.1016/j.legalmed.2015.06.005

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 胃幽門輪潰瘍穿孔の一例2015

    • Author(s)
      臼元洋介、鮫島直美、辻 彰子、池田典昭
    • Journal Title

      法医学の実際と研究

      Volume: 58 Pages: 139-144

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 心臓性突然死3例のエクソーム解析で得られた遺伝子変異について2014

    • Author(s)
      辻彰子、臼元洋介、池田典昭
    • Journal Title

      法医学の実際と研究

      Volume: 22 Pages: 214-215

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Medical neglect death due to acute lympholasticleukaemia2014

    • Author(s)
      Usumoto, Y., Sameshima, N., Ikeda, N.
    • Journal Title

      Fukuoka Acta Medica

      Volume: 105 Pages: 234-240

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification and characterization of a novel genetic mutation wih prolonged QT syndrome.2014

    • Author(s)
      Hata, Y., Ikeda, N., Nishida, N.
    • Journal Title

      Int J Legal Med

      Volume: 128 Pages: 105-115

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 腹腔鏡下スリーブ状胃切除術中に死亡した1剖検例2013

    • Author(s)
      臼元洋介、池田典昭他
    • Journal Title

      法医学の実際と研究

      Volume: 56 Pages: 181-186

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Responsibility for reporting patient death due to hospital error in Japan when an error occurred at a refering institution2013

    • Author(s)
      Shoichi Maeda, Noriaki Ikeda et al.
    • Journal Title

      Journal of Law and Medicine

      Volume: 21 Pages: 441-446

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 死体腸内容の16S rRNAメタゲノム解析2015

    • Author(s)
      辻 彰子、池田典昭
    • Organizer
      日本DNA多型学会
    • Place of Presentation
      岡山
    • Year and Date
      2015-11-19
    • Related Report
      2015 Annual Research Report
  • [Book] 救急・集中治療における臨床倫理2016

    • Author(s)
      池田典昭
    • Total Pages
      162
    • Publisher
      克誠堂出版
    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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