Predictive value of radioiodine therapy for the patients of differentiated thyroid cancer by measuring the concentraion of urinary iodine

• Project/Area Number: 25461809
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Nagoya University
• Principal Investigator: ITO Shinji 名古屋大学, 医学部附属病院, 助教 (50597846)
• Co-Investigator(Kenkyū-buntansha): 岩野 信吾 名古屋大学, 医学系研究科, 准教授 (90335034)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 分化型甲状腺癌 / 放射性ヨウ素内用療法 / ヨウ素摂取制限 / 尿中ヨウ素濃度 / サイログロブリン / 放射線ヨウ素内用療法 / 放射性ヨード内用療法 / ヨード摂取制限 / 甲状腺刺激ホルモン / ヨード制限

Outline of Final Research Achievements

The purpose of this study is to clarify the influence of low iodine diets performed before the radioiodine therapy for the patients of differentiated thyroid cancer, through measuring the concentration of urinary iodine. There were no significant differences between the concentrations of urinary iodine of the two methods of low iodine diets: self-management low iodine diet and ready-made packaged strict low iodine diet. The outcome of radioiodine therapy was also not affected by the methods of low iodine diet. The standard self-managed low diet which were conducted in Japan is suggested to be appropriate for the preparation for the radioiodine therapy.

Research Products

• [Presentation] 分化型甲状腺癌患者に対するI-131 1110MBqアブレーションの成否予測因子の検討 (2015)
  • Author(s): 伊藤 信嗣、岩野 信吾、加藤 克彦、長縄 慎二
  • Organizer: 第55回 日本核医学会学術総会
  • Place of Presentation: ハイアットリージェンシー東京 （東京都新宿区）
  • Year and Date: 2015-11-05
• [Presentation] Predictive factors for the outcome of I-131 1110MBq ablation therapy in the patients with differentiated thyroid cancer: urinary iodine, serum thyroglobulin, and uptake to thyroid bed (2015)
  • Author(s): Shinji Ito, Shingo Iwano, Katsuhiko Kato, and Shinji Naganawa
  • Organizer: Annual Congress of the European Association of Nuclear Medicine
  • Place of Presentation: Hamburg (Germany)
  • Year and Date: 2015-10-10
  • Int'l Joint Research
• [Presentation] 分化型甲状腺癌に対するI-131アブレーション：当施設における投与量30mCiと100mCiの比較検討 (2013)
  • Author(s): 伊藤信嗣、岩野信吾、加藤克彦、長縄慎二
  • Organizer: 日本核医学会第77回中部地方会
  • Place of Presentation: 金沢大学（金沢市）