Establishment of next generation cell therapy for diabetes on the prevascularization procedures with Adipose-Derived Stem Cell
Project/Area Number |
25461940
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
General surgery
|
Research Institution | Tohoku University |
Principal Investigator |
Inagaki Akiko 東北大学, 医学系研究科, 助教 (20360224)
|
Co-Investigator(Kenkyū-buntansha) |
後藤 昌史 東北大学, 医学系研究科, 教授 (50400453)
|
Project Period (FY) |
2013-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 膵島移植 / 血管新生 / 移植・再生医療 / 移植・再生医学 / 脂肪由来幹細胞 / 糖尿病 / 皮下移植 / 膵島 |
Outline of Final Research Achievements |
Subcutaneous islet transplantation is associated with minimal invasiveness, but poor vascularization. Thus, the optimization of the prevascularization procedures is crucial for improving the outcome. Therefore, in presence study, we evaluated the effectiveness of (Adipose-Derived Stem Cells: ADSC). Although the cure rates in the bFGF group were considerably higher than in the non-device and control group, but there was no significant difference among ADSC group and non-device group on the cure rate.
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Report
(5 results)
Research Products
(4 results)