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Prediction of the rupture risk of dissecting aortic aneurysm and development of Rupture potential index from PET (positron emission tomogramphy)

Research Project

Project/Area Number 25462156
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular surgery
Research InstitutionTohoku University

Principal Investigator

KUMAGAI Kiichiro  東北大学, 医学(系)研究科(研究院), 助教 (80396564)

Co-Investigator(Kenkyū-buntansha) SAIKI Yoshikatsu  東北大学, 大学院医学系研究科, 教授 (50372298)
MASUDA Shinya  東北大学, 大学院医学系研究科, 助教 (30596094)
MOTOYOSHI Naotaka  東北大学, 大学院医学系研究科, 非常勤講師 (40375093)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords有限要素解析 / PET / 破裂予測 / 大動脈解離 / 胸部大動脈瘤 / 液体力学 / 相当応力 / 大血管外科学
Outline of Final Research Achievements

Finite element analyses for degenerative thoracic aortic aneurysms were performed, and distributions of von Mises stresses and maximum stress were calculated. Positron emission tomogramphy (PET) of thoracoabdominal aortic aneurysms were performed in two rapid expanding aneurysms. Standard uptake value (SUV) of aneurysms was not so higher in these two cases. The relationship between von Mises stress and standard uptake value of aneurysm was not clear in two cases, and rupture risks could not predicted in this method. A new finite element model needed for the finite element analysis of aortic dissection. We developed a double barrel model from CT images of Stanford type B aortic dissection. Because of complex geometry of these dissecting aneurysms, we failed to calculate the von Mises stress of this model by structural analysis. Nevertheless, this model is applicable to fluids mechanics, and using this model we prepare to analyze the shear stress of dissecting aortic aneurysms.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2013

All Presentation (1 results)

  • [Presentation] Finite element analysis for thoracic aortic aneurysm: An attempt to predict a risk of rupture2013

    • Author(s)
      熊谷紀一郎
    • Organizer
      アジア心臓血管胸部外科学会
    • Place of Presentation
      神戸
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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