Development of novel therapy for the malignant meningioma by exploration of specific gene expression
Project/Area Number |
25462270
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Neurosurgery
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Research Institution | Kumamoto University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
Kuratsu Jun-ichi 熊本大学, 大学院生命科学研究部, 教授 (20145296)
Nakamura Hideo 熊本大学, 医学部附属病院, 講師 (30359963)
Hide Takuichiro 熊本大学, 医学部附属病院, 助教 (40421820)
Makino Keishi 熊本大学, 医学部附属病院, 講師 (90381011)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | 悪性髄膜腫 / マイクロRNA / 遺伝子発現 / マイクロアレイ / miRNA / 細胞増殖 / 腫瘍幹細胞 / アレイ分析 |
Outline of Final Research Achievements |
To establish a new therapy for malignant meningioma, the specific gene in malignant meningioma such as micro RNA and specific DNA were explored. Tow microRNA (miR488 and mrR335) and three DNA (ISLR, SDHAP1 and CNTNAP3) were expressed at a high rate.
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Report
(3 results)
Research Products
(11 results)
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[Journal Article] Can 3T MR angiography replace DSA for the identification of arteries feeding intracranial meningiomas?2013
Author(s)
Uetani H, Akter M, Hirai T, Shigematsu Y, Kitajima M, Kai Y, Yano S, Nakamura H, Makino K, Azuma M, Murakami R, Yamashita Y.
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Journal Title
American Journal of Neuroradiology
Volume: 34
Issue: 4
Pages: 765-772
DOI
Related Report
Peer Reviewed
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