Study of the factors associated with a cause and progression of idiopathic scoliosis
| Project/Area Number |
25462318
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Orthopaedic surgery
|
|---|
| Research Institution | Spinal Injuries Center |
|---|
Principal Investigator |
MAEDA TAKESHI 独立行政法人労働者健康福祉機構総合せき損センター(研究部), その他部局等, 研究員 (80315077)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
OKADA SEIJI 九州大学, 医学研究院, 准教授 (30448435)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | 特発性側弯症 / メカニズム１ |
|---|
| Outline of Final Research Achievements |
The factors associated with a cause and progression of idiopathic scoliosis remain unclear. We examined the relationship between the anteroposterior chest dimension and the Cobb angle in thoracic scoliosis patients, and found that there was a significant correlation between them. We further demonstrated that a rib cage deformity with an imbalanced load to the vertebral body resulted in progressive structural scoliosis by using mice model.
|
Report
(3 results)
Research Products
(10 results)
