Development of comprehensive seed implantation technique aiming for overcoming pubic bone interference during permanent brachytherapy in men with prostate cancer.

Research Project

Project/Area Number	25462498
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Multi-year Fund
Section	一般
Research Field	Urology
Research Institution	Kyoto Prefectural University of Medicine
Principal Investigator	Okihara Koji 京都府立医科大学, 医学(系)研究科(研究院), 准教授 (80285270)
Co-Investigator(Kenkyū-buntansha)	IWATA Tsuyoshi 京都府立医科大学, 医学研究科, 客員講師 (00552209) MIKI Tsuneharu 京都府立医科大学, 医学研究科, 特任教授 (10243239) KAMOI Kazumi 京都府立医科大学, 医学研究科, 講師 (40295663) SOH Jintetsu 明治国際医療大学, 医学教育センター, 教授 (40305587) HONGO Fimiya 京都府立医科大学, 医学研究科, 助教 (80291798) NAYA Yoshio 京都府立医科大学, 医学研究科, 講師 (80639881) KAWAUCHI Akihiro 滋賀医科大学, 医学部, 教授 (90240952)
Project Period (FY)	2013-04-01 – 2016-03-31
Project Status	Completed (Fiscal Year 2015)
Budget Amount *help	¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000) Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000) Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000) Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Keywords	前立腺癌 / 小線源治療 / 超音波 / 画像融合
Outline of Final Research Achievements	To overcome pubic bone interference during permanent brachytherapy, we have conducted two different kinds of methods; 1) Design angle-wide type template, and 2) Syncronization transperineal and transrectal view using real-virtual sonography (RVS) technique. As for the design new-type template, we additionnaly designed new templates, which was made of plastic material including hard type one after considering the drawbacks using aluminium materials. In results, we succeeded to puncture needle, maintaining accurate and up-forward angle. In consective experiments using RVS technique, it occurred more than 4 mm- magnetic errors, and we concluded it is difficult to apply the sycronize technique in the clinical setting.