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The wound healing system applied new antibiotic agent Firmocidin and eccrine sweat natural immunity

Research Project

Project/Area Number 25462795
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plastic surgery
Research InstitutionEhime University

Principal Investigator

Nakaoka Hiroki  愛媛大学, 医学部附属病院, 准教授 (30172266)

Co-Investigator(Kenkyū-buntansha) Murakami Masamoto  愛媛大学, 医学部附属病院, 講師 (20278302)
Co-Investigator(Renkei-kenkyūsha) Shirakata Yuju  愛媛大学, 医学部附属病院, 准教授 (50226320)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords創傷治癒 / 自然免疫 / エックリン汗 / エクリン汗 / 三次元表皮
Outline of Final Research Achievements

In a wound model of two-dimensional keratinocyte culture system and LSE, it was difficult to reproduce the bacterial infection model in the wound only with bacteria, keratinocyte, and antibacterial agents. The examination about the wound healing delay using the CRAMP knockout mise in vivo could not run, because continuous supply of Firmocidin from the colleague had been impossible. In vivo examination results may lead to the identification of desired cells. We wait for Firmocidin supply and are going to develop further examination continuously.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2015 2014 2013

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (2 results)

  • [Journal Article] 総論:小児の頭頚部母斑にどのように対処するか?2015

    • Author(s)
      中岡啓喜
    • Journal Title

      PEPARS

      Volume: 102 Pages: 13-18

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 汗と湿疹2015

    • Author(s)
      村上正基
    • Journal Title

      アレルギー・免疫

      Volume: 22 Pages: 63-68

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Case of plmoplantar pustulosis that developed with acute plomerulonephritis2015

    • Author(s)
      Murakami M, et al
    • Journal Title

      Dermatol.

      Volume: 231 Pages: 304-311

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Kasabach^Merritt症候群を併発し治療を行ったtufted angiomaの3例2014

    • Author(s)
      宝道麻由、中岡啓喜、森 秀樹、戸澤麻美
    • Journal Title

      日本形成外科学会会誌

      Volume: 34 Pages: 53-60

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 耳下腺部転移を認めた左前額部浸潤型基底細胞癌の1例2014

    • Author(s)
      中岡啓喜、寶道麻由、森 秀樹、戸澤麻美
    • Journal Title

      西日本皮膚科

      Volume: 76 Pages: 357-360

    • NAID

      130004695272

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 内頚静脈血栓症により静脈血流不全をきたした遊離皮弁の1例2014

    • Author(s)
      中岡啓喜、森 秀樹、戸澤麻美
    • Journal Title

      日本頭蓋顎顔面外科学会誌

      Volume: 30 Pages: 200-205

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 骨盤内動静脈奇形の2治験例:Interventional Radiology下の硬化療法と切除術2013

    • Author(s)
      中岡啓喜、森 秀樹、戸澤麻美
    • Journal Title

      日本形成外科学会会誌

      Volume: 33 Pages: 524-528

    • NAID

      10031189549

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 皮膚原発epithelioid hemangioendothelioma(EHE)の1例2013

    • Author(s)
      戸澤麻美、森 秀樹、中岡啓喜
    • Journal Title

      Skin Cancer

      Volume: 28 Pages: 329-335

    • NAID

      130004697527

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] 顔面腫瘍(瘤)の分類と特徴 -受診世代による分類とその特徴-2013

    • Author(s)
      中岡啓喜
    • Journal Title

      形成外科

      Volume: 56 Pages: 367-376

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 当院における脈管性病変に対する形成外科、皮膚科医の認識について2014

    • Author(s)
      中岡啓喜、森 秀樹、戸澤麻美、三宅啓介
    • Organizer
      第10回血管腫・血管奇形研究会
    • Place of Presentation
      信州大学医学部(松本市)
    • Year and Date
      2014-07-20
    • Related Report
      2014 Research-status Report
  • [Presentation] 皮膚悪性腫瘍の診断 治療における留意点とピットフォール2014

    • Author(s)
      中岡啓喜
    • Organizer
      第56回日本形成外科学会
    • Place of Presentation
      長崎ブリックホール(長崎市)
    • Year and Date
      2014-04-11
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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