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Development of MR microscope for the squamous carcinoma in the oral cavity

Research Project

Project/Area Number 25462910
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Pathobiological dentistry/Dental radiology
Research InstitutionHokkaido University

Principal Investigator

Minowa Kazuyuki  北海道大学, 歯学研究科, 教授 (30209845)

Co-Investigator(Kenkyū-buntansha) 藤間 憲幸  北海道大学, 大学病院, 助教 (80431360)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
KeywordsQSI / 拡散強調像 / 口腔癌 / 扁平上皮癌 / DWI / b-factor / ADC / 頭頸部癌
Outline of Final Research Achievements

The aim of our study is to develop the MR microscope that non-invasively will be able to visualize pathological information of the squamous cell carcinoma in the oral cavity by Q space image technique belonging to the diffusion weighted images. The parameter of the Q space imaging technique was established for this study. The comparison between the parameter of the Q space imaging and specimen of the squamous cell carcinoma in the oral cavity, also between the parameter of the Q space imaging and routine diagnostic image for the oral cancer were evaluated.
The correlations between some of the parameters in the Q space imaging and cell growth factor, routine diagnostic image for the oral cavity cancer were obtained.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (15 results)

All 2017 2016 2015 2014 2013

All Journal Article (9 results) (of which Peer Reviewed: 8 results,  Open Access: 6 results,  Acknowledgement Compliant: 4 results) Presentation (4 results) (of which Invited: 3 results) Book (2 results)

  • [Journal Article] 口腔がん再建術後に中心静脈カテーテル関連深部静脈血栓を生じた2例2017

    • Author(s)
      秦 浩信
    • Journal Title

      口腔腫瘍

      Volume: 29 Pages: 1-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] エナメル上皮腫の画像診断に関して2016

    • Author(s)
      箕輪和行
    • Journal Title

      口腔腫瘍

      Volume: 28 Pages: 256-263

    • Related Report
      2016 Annual Research Report
  • [Journal Article] クローズドロックに継続する前歯部開口の臨床的特徴2016

    • Author(s)
      後藤田章人
    • Journal Title

      日本補綴誌

      Volume: 8 Pages: 281-288

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 最近8年間に北海道大学病院歯科放射線科が対応した歯科異物に誤嚥および誤飲疑い症例の実態調査2016

    • Author(s)
      金子正範、山野茂、塚原亜希子、志摩朋香、鈴鹿正顕、大森桂一、箕輪和行
    • Journal Title

      北海道歯学会雑誌

      Volume: 36 Pages: 72-81

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 精神発達遅滞を有する進行口腔がん患者への外科治療経験2015

    • Author(s)
      日笠紘志、榊原典幸、水野貴行、加藤卓巳、箕輪和行、高野昌士
    • Journal Title

      北海道歯学会雑誌

      Volume: 36 Pages: 14-20

    • NAID

      120005676288

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Intravoxel incoherent motion diffusion-weighted imaging in head and neck squamous cell carcinoma: assessment of perfusion-related parameters compared to dynamic contrast-enhanced MRI2014

    • Author(s)
      Fujima N, Yoshida D, Sakashita T, Homma A, Tsukahara A, Tha KK, Kudo K, Shirato H.
    • Journal Title

      Magn Reson Imaging

      Volume: 32 Pages: 1206-1213

    • NAID

      120005527830

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Arterial spin labeling to determine tumor viability in head and neck cancer before and after treatment.2014

    • Author(s)
      Fujima N, Kudo K, Yoshida D, Homma A, Sakashita T, Tsukahara A, Tha KK, Zaitsu Y, Terae S, Shirato H.
    • Journal Title

      J Magn Reson Imaging.

      Volume: 40 Pages: 920-928

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] A case of pigmented villonodullar synovitis with few clinical symptoms arising from the temporomandibular joint2013

    • Author(s)
      k Okada, T Yamaguchi,K Minowa,Y Totsuka, M Shinndo, N Inoue
    • Journal Title

      Oral radiology

      Volume: 29 Pages: 74-79

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Magnetic displacement force and torque on dental keepers in the static magnetic field of MR scanner2013

    • Author(s)
      M Omatsu, T Obata, K Minowa, K Yokosawa, E Inagaki, K Ishizaka, K Shibayama, T Yamamoto
    • Journal Title

      J magnetic resonance imaging

      Volume: 20 Pages: 1-6

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 歯科臨床画像診断2016

    • Author(s)
      箕輪和行
    • Organizer
      北海道歯学会
    • Place of Presentation
      札幌、北海道大学歯学部講堂
    • Year and Date
      2016-03-03
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] エナメル上皮腫の画像診断2016

    • Author(s)
      箕輪和行
    • Organizer
      口腔腫瘍学会
    • Place of Presentation
      横浜、横浜市開港記念会館
    • Year and Date
      2016-01-22
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 術後照射における強度変調放射線治療(IMRT)の有用性2016

    • Author(s)
      鈴鹿正顕
    • Organizer
      口腔腫瘍学会
    • Place of Presentation
      横浜、横浜市開港記念会館
    • Year and Date
      2016-01-21
    • Related Report
      2015 Research-status Report
  • [Presentation] 口腔癌再発の画像診断2014

    • Author(s)
      箕輪和行
    • Organizer
      第32回 日本口腔腫瘍学会
    • Place of Presentation
      札幌コンベンションセンター(札幌市)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Book] エナメル上皮腫の診療ガイドライン2016

    • Author(s)
      箕輪和行
    • Total Pages
      66
    • Publisher
      学術社
    • Related Report
      2015 Research-status Report
  • [Book] 頭頸部画像診断2014

    • Author(s)
      箕輪和行
    • Total Pages
      176
    • Publisher
      医歯薬出版
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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