• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of the method for prevention of dental caries with antibacterial ammonium hexafluorosilicate

Research Project

Project/Area Number 25462961
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

SUGE Toshiyuki  徳島大学, 大学病院, 講師 (60243713)

Co-Investigator(Kenkyū-buntansha) HOSOKAWA Ikuko  徳島大学, 大学院医歯薬学研究部, 助教 (50707908)
TAKAHASHI Kanako  徳島大学, 病院, 特任講師 (80403715)
Co-Investigator(Renkei-kenkyūsha) ISHIKAWA Kunio  九州大学, 大学院歯学研究院, 教授 (90202952)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsフッ化ジアミンシリケート / フッ化ジアンミン銀 / 齲蝕 / 酸蝕症 / 抗菌成分 / フッ素 / 象牙質知覚過敏症 / 塩化セチルピリジニウム / 歯学 / ハイドロキシアパタイト / サホライド / 抗菌性 / S. mutans / 酸蝕歯 / グルコン酸クロルヘキシジン / 象牙質
Outline of Final Research Achievements

Diamine silver fluoride (Saforide) is clinical use for prevent of progress of dental caries and desensitizing for hypersensitive tooth. Unfortunately, diamine silver fluoride stained tooth black due to silver deposition. To overcome this drawback, ammonium hexafluorosilicate was prepared. Comparing the antibacterial activity, ammonium hexafluorosilicate seems to be inferior to diamine silver fluoride. To increase the antibacterial activity of ammonium hexafluorosilicate, several antibacterial agents have been added to ammonium hexafluorosilicate solution. The antibacterial activity of ammonium hexafluorosilicate with the addition of antibacterial agents was increased, therefore, ammonium hexafluorosilicate is useful for prevention of dental caries.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (3 results)

All 2015 2014

All Journal Article (1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] 象牙質知覚過敏症の病態と治療法2014

    • Author(s)
      菅俊行
    • Journal Title

      四国歯学会雑誌

      Volume: 26 Pages: 55-60

    • NAID

      120005832486

    • Related Report
      2013 Research-status Report
  • [Presentation] Fluorine activity of antibacterial ammonium hexafluorosilicate solution for the prevention of dental caries2015

    • Author(s)
      Toshiyuki Suge
    • Organizer
      Asia Pacific Dental Congress 2015
    • Place of Presentation
      Santec(シンガポール)
    • Year and Date
      2015-04-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Fluorine activity of antibacterial ammonium hexafluorosilicate solution for the prevention of dental caries2014

    • Author(s)
      Toshiyuki Suge
    • Organizer
      International Conference on Antimicrobial Research 2014
    • Place of Presentation
      マドリード(スペイン)
    • Year and Date
      2014-10-02
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi