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Development of simple and certain ingredient analysis methods for the intraoral metallic restorations in patients with allergic reactions to the dental alloys.

Research Project

Project/Area Number 25463034
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionThe Nippon Dental University College at Tokyo (2014-2015)
The Nippon Dental University (2013)

Principal Investigator

KOIKE Mari  日本歯科大学東京短期大学, その他部局等, 教授 (00234667)

Co-Investigator(Kenkyū-buntansha) GAKUSHIN HANAKO  日本歯科大学, 生命歯学部, 教授 (50226114)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords歯科用金属アレルギー / 歯科用合金 / 金属成分分析 / 歯科用ポイント / 切削用ポイント
Outline of Final Research Achievements

Dental restorations are commonly made of metals or alloys. Allergic reactions caused by dental restorations have increasingly been reported for various types of alloys. Metallic elements that are often used in dental alloys include: precious metals, cobalt, chromium, molybdenum and precious metals and also some minor alloying elements such as gallium, silicone, niobium, tantalum, tungsten, etc. Sometimes, one or more of these elements act as an allergen. Therefore, it is imperative to identify which element(s) in a restoration causes the reaction. It would be beneficial to patients if one could know which elements are included in their restorations without destruction. Our study showed that a non-destructive sampling method using specially developed abrasive devices were suitable for the chemical analysis of the metal samples retrieved on the surfaces of the device. In addition, the osmium coating to the samples were beneficial for the elemental analysis.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results,  Open Access: 1 results) Presentation (6 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] 金属アレルギー患者における診断・治療法に関するプロジェクト研究:歯科用金属による金属アレルギーの臨床病態と補綴学的対応に関する多施設調査2015

    • Author(s)
      細木真紀,田上直美,渡邉 恵,山瀬 勝,飯田俊二,舞田健夫,大平千之,大久保力廣,秋葉陽介,服部正巳,峯 篤史,高 永和,鳥井克典,松香芳三,志賀 博,市川哲雄
    • Journal Title

      日本歯科医学会誌

      Volume: 34 Pages: 44-48

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 歯科用金属の成分分析時における蒸着の効果2014

    • Author(s)
      小池麻里,志賀博,三橋扶佐子
    • Journal Title

      日本歯科大学東京短期大学雑誌

      Volume: 4 Pages: 106-112

    • NAID

      40020270978

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Abrasive Devices Deemed Suitable for Sampling Metallic Restorations in Vivo2016

    • Author(s)
      M. Koike, SK. Hummel, RJ. Mitchell, T. Okabe
    • Organizer
      AADR/CADR Annual Meeting & Exibition
    • Place of Presentation
      Los Angeles, California
    • Year and Date
      2016-03-16
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 口腔内にある修復物の成分元素を分析する方法の紹介2016

    • Author(s)
      小池麻里,小口春久
    • Organizer
      第69回レアメタル研究会,第3階貴金属シンポジウム
    • Place of Presentation
      東京大学生産技術研究所
    • Year and Date
      2016-01-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] Improved detectability of adhered metallic elements with osmium coating2015

    • Author(s)
      Koike Mari, Susan K. Hummel
    • Organizer
      93rd General Session & Exhibition of the IADR
    • Place of Presentation
      Boston, Mass., USA
    • Year and Date
      2015-03-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 異なる採取方法が金属成分分析に与える影響

    • Author(s)
      小池麻里,志賀 博,三橋扶佐子.
    • Organizer
      平成25年度日本補綴歯科学会東京支部学術講演会
    • Place of Presentation
      日本大学桜門会館3階 (東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] 全身症状を伴った金属アレルギー患者における口腔内修復金属同定法の検討

    • Author(s)
      小池麻里,志賀 博
    • Organizer
      第23回日本全身咬合学会学術大会
    • Place of Presentation
      日本大学桜門会館3階 (東京都)
    • Related Report
      2013 Research-status Report
  • [Presentation] Detecting Alloy Constituents from Adhered Metal on Abrasive Points

    • Author(s)
      Mari Koike, Susan K Hummel, Hiroshi Shiga
    • Organizer
      43rd Annual Meeting & Exhibition of the American Accociation of Dental Research
    • Place of Presentation
      Charollte Convention Center, USA
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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