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4D Registration of small animals to analyze brain function

Research Project

Project/Area Number 25540130
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Life / Health / Medical informatics
Research InstitutionTohoku University

Principal Investigator

HASHIMOTO Koicihi  東北大学, 情報科学研究科, 教授 (80228410)

Co-Investigator(Renkei-kenkyūsha) TABATA Testuya  東京大学, 分子細胞生物学研究所, 教授 (10183865)
HIROI Makoto  東京大学, 分子細胞生物学研究所, 教授 (80597831)
FEI Xianfeng  東北文化学園大学, 科学技術学部, 准教授 (20620470)
ARAI Shogo  東北大学, 大学院情報科学研究科, 助教 (80587874)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords蛍光画像 / 画像処理 / 4次元解析 / 生体情報 / ビジュアルサーボ / 位相限定法 / 3次元画像
Outline of Final Research Achievements

Memory analysis of fruit fly has long history. Recently developments of fluorescent probes have succeeded to analyze the neural circuit with one cell level. This research is to develop a image alignment technology to stack the fluorescent images obtained by two photon microscope. In 2013 FY we have developed an alignment program to precisely match two images. In 2014 FY we have successfully stack many images to make a 3D analysis and presented a paper in a journal.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2014 2013

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results)

  • [Journal Article] Lock-on Tracking Microscope2014

    • Author(s)
      橋本浩一
    • Journal Title

      Journal of the Robotics Society of Japan

      Volume: 32 Issue: 9 Pages: 784-788

    • DOI

      10.7210/jrsj.32.784

    • NAID

      130004707665

    • ISSN
      0289-1824, 1884-7145
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Regulation of Experience-Dependent Bidirectional Chemotaxis by a Neural Circuit Switch in Caenorhabditis elegans2014

    • Author(s)
      Yohsuke Satoh, Hirofumi Sato, Hirofumi Kunitomo, Xianfeng Fei, Koichi Hashimoto, Yuichi Iino
    • Journal Title

      The Journal of Neuroscience

      Volume: 34 Issue: 47 Pages: 15631-15637

    • DOI

      10.1523/jneurosci.1757-14.2014

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Feedback regulation of microscopes by image processing.2013

    • Author(s)
      Tsukada, Y., Hashimoto, K.
    • Journal Title

      Develop Growth Differ.

      Volume: 55 Issue: 4 Pages: 550-562

    • DOI

      10.1111/dgd.12056

    • NAID

      40019735215

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Principal component analysis of odor coding at the level of third-order olfactory neurons in Drosophila.2013

    • Author(s)
      Hiroi M, Ohkura M, Nakai J, Matsuda N, Hashimoto K, Inoue K, Fiala A, *Tabata T
    • Journal Title

      Genes Cells

      Volume: 18 Issue: 12 Pages: 1070-1081

    • DOI

      10.1111/gtc.12094

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Frame Synchronization of High-Speed Vision Sensors with Respect to Temporally Encoded Illumination in Highly Dynamic Environments2013

    • Author(s)
      Lei Hou, Shingo Kagami, Koichi Hashimoto
    • Journal Title

      Sensors

      Volume: Vol. 13, No. 4 Issue: 4 Pages: 4102-4121

    • DOI

      10.3390/s130404102

    • Related Report
      2013 Research-status Report
    • Peer Reviewed

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Published: 2014-07-25   Modified: 2019-07-29  

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