| Project/Area Number |
25560066
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Eating habits
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| Research Institution | National Agriculture and Food Research Organization |
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Principal Investigator |
OIKE Hideaki 独立行政法人農業・食品産業技術総合研究機構, 食品総合研究所・食品機能研究領域, 主任研究員 (30455307)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 老化 / 加齢性難聴 / マウス / 食事 / 乳酸菌 / 卵黄 / 食生活 / 高脂肪食 / カフェイン / アルコール / ABR |
|---|
| Outline of Final Research Achievements |
We established a evaluation method for anti-aging food factors by measuring age-related hearing loss (AHL) in mice. Drinking of alcohol, caffeine, or artificial sweeteners for 6 months did not affect onset of AHL, however, intake of high fat diets delayed onset of AHL. Shift of meal-timing for 3 months did not affect AHL. Neither deletion of Tas1R3 gene, which code a taste receptor for sweet and umami, altered onset of AHL.
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