| Project/Area Number |
25560210
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HASHIMOTO Takeshi 立命館大学, スポーツ健康科学部, 准教授 (70511608)
IWANAKA Nobumasa 立命館大学, 立命館グローバル・イノベーション研究機構, 研究員 (80584002)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | ナノバイオシステム / 脂肪細胞 / バイオチップ |
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| Outline of Final Research Achievements |
This study aimed to construct a system for programmable culture, measurement, and control of fat cell on a MEMS chip. We focused on development of the MEMS chip for fat cell culture as well as systemization. A MEMS chip was integrated with supply function of culture medium and chemical solutions. Three layers of polymers were bonded to form wells and channels in a chip. Several culture wells were prepared on a chip of 40mm square. A constructed system was equipped with a controller of supply of culture medium and chemical solutions. It has also become possible to capture microscopic images of cultured fat cell. Measurement results were feedback to control conditions of cultured fat cell through a computer. Real fat cell was successfully cultured and controlled by our system. As a result, developed efficient system for controllable cell culture will contribute to further investigation of fat cell.
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