Development of New Synthetic Reactions Based on Generation of Organometallic Species of Unstable Valency
| Project/Area Number |
25620034
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Organic chemistry
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| Research Institution | Tokyo University of Science, Yamaguchi |
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Principal Investigator |
Hojo Makoto 山口東京理科大学, 工学部, 教授 (50229150)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | Rieke亜鉛 / 還元 / 不飽和結合 / 還元的二量化 / 還元的環化 / α,β-不飽和カルボニル化合物 |
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| Outline of Final Research Achievements |
It was found that reductive dimerization of α,β-unsaturated esters at β-position took place in Rieke zinc Zn*-LDBB (lithium di-tert-butylbiphenylide) system to afford the corresponding adipates. Reductive cyclization reactions of bis-enoates, keto-enoates, and keto-alkenes were also found in the Zn*-LDBB system. These reactions are thought to proceed through chain mechanism based on high one-electron reducing ability of Rieke zinc toward radical anion generated from substrate.
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Report
(4 results)
Research Products
(2 results)
