| Project/Area Number |
25630220
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Civil and environmental engineering
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
DAISUKE Sano 北海道大学, 工学(系)研究科(研究院), 准教授 (80550368)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
WATANABE Kozo 愛媛大学, 理工学研究科, 准教授 (80634435)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 胃腸炎ウイルス / 消毒 / 耐性 / 水処理 / 適応進化 / 遊離塩素 / ノロウイルス / 上水 / 下水 / 塩素消毒 / 繰り返し曝露 / 消毒剤耐性 / カプシドタンパク質 / アミノ酸変異 |
|---|
| Outline of Final Research Achievements |
The objective of this study was to investigate the mechanism of acquiring free chlorine-resistance of noroviruses. As a result, it was confirmed that a population of murine norovirus acquired the relatively high resistance against free chlorine treatment by repeatedly exposing to free chlorine, owing to the dominance of free chlorine-resistant mutants in the population. Based on these results, the project leader was honored (Encouraging Award for Young Researchers) in the 55th Conference of Japanese Society of Clinical Virology.
|
