Elucisation of the mechanisms of disinfection resistance of gastroenteritis viruses
| Project/Area Number |
25630220
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Civil and environmental engineering
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| Research Institution | Hokkaido University |
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Principal Investigator |
DAISUKE Sano 北海道大学, 工学(系)研究科(研究院), 准教授 (80550368)
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| Co-Investigator(Kenkyū-buntansha) |
WATANABE Kozo 愛媛大学, 理工学研究科, 准教授 (80634435)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 胃腸炎ウイルス / 消毒 / 耐性 / 水処理 / 適応進化 / 遊離塩素 / ノロウイルス / 上水 / 下水 / 塩素消毒 / 繰り返し曝露 / 消毒剤耐性 / カプシドタンパク質 / アミノ酸変異 |
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| Outline of Final Research Achievements |
The objective of this study was to investigate the mechanism of acquiring free chlorine-resistance of noroviruses. As a result, it was confirmed that a population of murine norovirus acquired the relatively high resistance against free chlorine treatment by repeatedly exposing to free chlorine, owing to the dominance of free chlorine-resistant mutants in the population. Based on these results, the project leader was honored (Encouraging Award for Young Researchers) in the 55th Conference of Japanese Society of Clinical Virology.
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Report
(3 results)
Research Products
(6 results)
