| Project/Area Number |
25650120
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | National Institute of Genetics |
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Principal Investigator |
Muto Akira 国立遺伝学研究所, 個体遺伝研究系, 助教 (00525991)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | ゼブラフィッシュ / カルシウムイメージング / 捕獲行動 / 視覚系 / ゾウリムシ / 摂食行動 / 視床下部 / 前視蓋 / 神経 / 脳 |
|---|
| Outline of Final Research Achievements |
We explored neuronal activity in the zebrafish larval brain to identify neural cells that were involved in prey capture behavior. We observed neuronal activity in the inferior lobes of the hypothalamus (ILH) that was related to visual perception of prey. Suppression of the ILH activity by neurotoxin significantly reduced prey capture activity.Furthermore, we also found that the pretecal neurons, which was responsible for visual prey detection, projected their axons to the ILH. Thus, we demonstrated thatpretecto-hypothalamic circuit has a crucial role in visual prey detection and feeding behavior in zebrafish.
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