| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
In this study, we screened and characterized factors affecting chronological lifespan in fission yeast to gain insight how the lifespan of cell is regulated. We have succeeded to identify some novel factors whose recessive mutations result in the elongation of lifespan. Therefore if we could find reagent that inhibits function of the novel factor, we might be able to elongate fission yeast lifespan by treatment with such reagent. We also found genes whose over-expression result in the elongation of lifespan. Here we could accumulate basic knowledge for lifespan regulation of fission yeast.
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