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An Attempt to Establish the Technology for Estimating Real Irradiated Dose of Particle Therapy in a Living Body

Research Project

Project/Area Number 25670527
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionGunma University

Principal Investigator

KATOH Hiroyuki  群馬大学, 重粒子線医学推進機構, 助教 (30334121)

Co-Investigator(Kenkyū-buntansha) SHIRAI Katsuyuki  群馬大学, 医学(系)研究科(研究院), 講師 (10400748)
KAWAMURA Hidemasa  群馬大学, 医学(系)研究科(研究院), 講師 (80431716)
OKAMOTO Masahiko  群馬大学, 医学部附属病院, 講師 (10451725)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords放射線治療 / 粒子線治療 / 線量分布 / QA/QC / 重粒子線治療 / 自己放射化PET
Outline of Final Research Achievements

In our study, we showed that MRI(T2WI) signal intensity of area irradiated higher dose was changed higher intensity one year after carbon-ion radiotherapy for prostate cancer. We measured iso-center dose profiles of estimating dose in treatment planning system and iso-center signal intensity profiles of MRI(T2WI) scanned one year after irradiation. We analyzed both of profiles and we got the relationship among them. This study shows the possibility to develop the technology for estimating a real irradiated dose of particle therapy in a living body without invasive.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014 Other

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (2 results) (of which Int'l Joint Research: 2 results) Remarks (2 results)

  • [Journal Article] Changes in Rectal Dose Due to Alterations in Beam Angles for Setup Uncertainty and Range Uncertainty in Carbon-Ion Radiotherapy for Prostate Cancer2016

    • Author(s)
      Yoshiki Kubota, Hidemasa Kawamura, Makoto Sakai, Ryou Tsumuraya, Mutsumi Tashiro, Ken Yusa, Nobuteru Kubo, Hiro Sato, Masahiro Kawahara, Hiroyuki Katoh, Tatsuaki Kanai, Tatsuya Ohno, Takashi Nakano
    • Journal Title

      PLOS ONE

      Volume: April Issue: 4 Pages: 1-11

    • DOI

      10.1371/journal.pone.0153894

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Incidence, risk factors, and dose-volume relationship of radiation-induced rib fracture after carbon ion radiotherapy for lung cancer2016

    • Author(s)
      Abe T, Shirai K, Saitoh J, Ebara T, Shimada H, Tashiro M, Okano N, Ohno T, Nakano T
    • Journal Title

      Acta Oncol.

      Volume: 55 Issue: 2 Pages: 163-166

    • DOI

      10.3109/0284186x.2015.1088169

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 重粒子線単独治療を行った前立腺癌症例における治療後1年間のPSA値の変化2014

    • Author(s)
      加藤弘之、河村英将、村田和俊、神沼拓也、石川仁、松井博、伊藤一人、鈴木和浩、大野達也、中野隆史
    • Journal Title

      泌尿器外科

      Volume: Vol.27 Pages: 1361-1363

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 重粒子線治療2014

    • Author(s)
      加藤弘之、大野達也
    • Journal Title

      臨床腫瘍プラクティス

      Volume: Vol.10 Pages: 312-315

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Carbon-ion Beam Range Verification Using the Muscular Intensity Changes of the Magnetic Resonance Image2015

    • Author(s)
      Masahiro Kawahara, Hiroyuki Katoh, Hidemasa Kawamura, Nobuteru Kubo, Hiro Tatsuaki Kanai, Takashi Nakano
    • Organizer
      Particle Therapy Co-Operative Group 54th Annual Conference
    • Place of Presentation
      San Diego, United States
    • Year and Date
      2015-05-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Comparison of dose distributions between carbon ion beam and IMRT in locally advanced pancreas cancer2015

    • Author(s)
      Mashiko Okamoto, Hiroki Kiyohara, Kyohei Fukata, Naoko Okano, Keitaro Hirai, Kenichiro Araki, Izumi Takeyoshi, Tatsuya Ohno, Takashi Nakano
    • Organizer
      Particle Therapy Co-Operative Group 54th Annual Conference
    • Place of Presentation
      San Diego, United States
    • Year and Date
      2015-05-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Remarks] EQD Calculator

    • URL

      http://developer37jp.wix.com/eqdcalculator-en

    • Related Report
      2015 Annual Research Report
  • [Remarks] TDF Calculator

    • URL

      http://developer37jp.wix.com/tdfcalculator-en

    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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