| Project/Area Number |
25670537
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
FUJII Hirotada 札幌医科大学, 医療人育成センター, 教授 (70209013)
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| Co-Investigator(Renkei-kenkyūsha) |
AKABA Hideo 大阪大学大学院, 基礎工学研究科, 准教授 (00552077)
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| Project Period (FY) |
2013-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 視覚化 / イメージング / EPR / ESR / ストレス |
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| Outline of Final Research Achievements |
Electron Paramagnetic Resonance Imaing (EPRI) combinded with nitroxide imaging probes is known to be a powerful non-invasive method for visualizating the redox status in vivo. Recently we have improved teh conventional L-band EPR imager using the rapid-scan technique, and it becomes possible to obtain three-dimensional EPR images of small rodents. Using this improved EPR imager, simultaneous imaging of multiple bio-functions, such as redox status, oxygen concnetration, and pH, was carried out non-invasively.
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