• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The study of lung regenerative medicine for the damaged lung by iPS cells

Research Project

Project/Area Number 25670606
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Respiratory surgery
Research InstitutionChiba Cancer Center (Research Institute) (2015-2016)
Chiba University (2013-2014)

Principal Investigator

YAMAMOTO Takayoshi  千葉県がんセンター(研究所), 呼吸器外科, 医長 (20648349)

Research Collaborator SHIINA Yuuki  千葉大学, 大学院医学研究院, 医員 (30782304)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords肺再生 / iPS / マウス / 肺移植 / iPS細胞 / 2型肺胞上皮細胞 / II型肺胞上皮細胞
Outline of Final Research Achievements

The purpose is that we differentiate and induce the alveolar type Ⅱ cell. We transplant these cells to disease model mouse by air way and discuss the effect.
In this duration, we could stable passage the mouse iPS cells and human iPS cells and produce the medium to differentiate and induce to the alveolar type Ⅱ cells. And we made the specific gene which could label the SP-C protein.
We now make the ischemic and reperfusion mouse model, we continue to make the experiments of the chronic immunological rejection model mouse by allograft lung transplantation.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (1 results)

All 2014

All Presentation (1 results)

  • [Presentation] iPS細胞による2型肺胞上皮細胞の誘導の試み2014

    • Author(s)
      山本高義、坂入祐一、稲毛輝長、尹貴正、田中教久、鎌田稔子、森本淳一、中島崇裕、鈴木秀海、田川哲三、岩田剛和、溝渕輝明、吉田成利、吉野一郎
    • Organizer
      第1262回千葉医学会 平成26年度第13回 千葉大学大学院医学研究院 呼吸器病態外科学 教室例会
    • Place of Presentation
      千葉大学亥鼻キャンパス薬学部120周年記念講堂
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi