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The mechanism to obtain undifferentiated ability by making aggregate

Research Project

Project/Area Number 25670754
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionKeio University

Principal Investigator

KAZUO Kishi  慶應義塾大学, 医学部, 教授 (40224919)

Co-Investigator(Kenkyū-buntansha) ARAMAKI Noriko  慶應義塾大学, 医学部, 講師 (80365311)
HAYASHI Ruka  慶應義塾大学, 医学部, 助教 (50445392)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords再生 / 皮膚 / 未分化 / 幹細胞 / 毛包
Outline of Final Research Achievements

This study aimed to find out the mechanism of getting undifferentiated ability by making aggregates. In mouse fibroblasts, undifferentiated markers were upregulated by making aggregates. The levels of undifferentiated markers were, however, differs in between each clones. Surrounding conditions were thought to affect the expression levels of these undifferentiated markers.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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