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Regulation and reconstruction of acquired memories in human microbiota

Research Project

Project/Area Number 25670776
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Morphological basic dentistry
Research InstitutionKyoto University (2014)
Tokyo Medical and Dental University (2013)

Principal Investigator

MARUYAMA Fumito  京都大学, 医学(系)研究科(研究院), 准教授 (30423122)

Co-Investigator(Kenkyū-buntansha) NAKAGAWA Ichiro  京都大学, 大学院医学研究科, 准教授 (70294113)
KUROKAWA Ken  東京工業大学, 地球生命研究所, 准教授 (20343246)
MIMURO Hitomi  東京大学, 医科学研究所, 准教授 (80396887)
Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsバクテリオファージ / CRISPR / 微生物生態学 / 細菌叢解析 / 外来因子
Outline of Final Research Achievements

Distribution and structure of the CRISPR, acquired immune mechanisms of bacteria, to bacteriophages, in human microbial flora are assumed that controls the robustness of its flora. As a result, CRISPR unexpectedly exist on the bacteriophage, which has been thought to not be able to coexist. It was revealed that CRISPR are distributed actually in broad range of bacterial species. This indicates that it is necessary to introduce a new concept in helping to continue to clear the robustness of the bacterial flora.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (2 results)

All Other

All Remarks (2 results)

  • [Remarks] 微生物感染症学

    • URL

      http://www.bac.med.kyoto-u.ac.jp/index.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] 東京医科歯科大学大学院医歯学総合研究科細菌感染制御学分野ホームページ

    • URL

      http://www.tmd.ac.jp/grad/bac/index.html

    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

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