The evolution of genetical assessment for persistent apical periodontitis.
Project/Area Number |
25670809
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Research Category |
Grant-in-Aid for Challenging Exploratory Research
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Allocation Type | Multi-year Fund |
Research Field |
Conservative dentistry
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Research Institution | Osaka University |
Principal Investigator |
Itoh Shousaku 大阪大学, 歯学部附属病院, 講師 (90360495)
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Project Period (FY) |
2013-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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Keywords | 根尖性歯周炎 / IL-1B / SNP / 難治性根尖性歯周炎 / SNPs / 難治根尖性歯周炎 |
Outline of Final Research Achievements |
The aim of this study is to investigate the relationship between persistent apical periodontitis and SNP of inflammatory cytokine, IL-1B. We investigated the relationship of the SNP in the intron of IL-1B, SNPID:rs1143643. Though the previous reports, from Caucasoid, showed the relationship between the SNP in the intron of IL-1B and persistent apical periodontitis, our study, from Mongoloid, showed no relationship. We concluded that the efficacy of SNP were different among the racial difference, such as Mongoloid and Caucasoid.
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Report
(4 results)
Research Products
(10 results)
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[Journal Article] First mouse model for combined osteogenesis imperfecta and ehlers-danlos syndrome.2014
Author(s)
Chen F, Guo R, Itoh S, Moreno L, Rosenthal E, Zappitelli T, Zirngibl RA, Flenniken A, Cole W, Grynpas M, Osborne LR, Voge W, Adamson L, Rossant J, Aubin JE
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Journal Title
Journal of Bone and Mineral Research
Volume: 29
Issue: 6
Pages: 1412-1423
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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