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Prevalence and clinical features of restless legs syndrome among Japanese pregnant women

Research Project

Project/Area Number 25670973
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Lifelong developmental nursing
Research InstitutionNagasaki University

Principal Investigator

ETO Hiromi  長崎大学, 医歯薬学総合研究科(保健学科), 教授 (10213555)

Co-Investigator(Kenkyū-buntansha) OKA Yasunori  愛媛大学, 医学部附属病院, 准教授 (60419025)
Co-Investigator(Renkei-kenkyūsha) HORIUCHI Shigeko  聖路加国際大学, 看護学部, 教授 (70157056)
NISHIHARA Kyoko  (公財)労働科学研究所, 研究員 (80172683)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords乳児 / 妊婦 / フェリチン / 睡眠時周期性四肢運動 / RLS / 鉄 / 葉酸 / 乳幼児突然死症候群 / 周産期アウトカム
Outline of Final Research Achievements

Aims: To determine the prevalence of restless legs syndrome (RLS) among Japanese pregnant women, and clarify correlation between RLS and clinical outcomes. Methods: RLS screening was conducted using the Johns Hopkins Telephone Diagnostic Interview for low-risk 140 and high-risk 81 pregnant women in their third trimester. Blood test and biochemistry results, and delivery outcomes were compared between the RLS group and the control group. Results: RLS was experienced by 22 (15.7%) of the 140 women, and 14 (17.3%) of the 81 women. No significant difference was found for hemoglobin, serum ferratin, serum folate levels and delivery outcomes between the RLS group and the control group. Conclusion: The prevalence of RLS was high in Japanese pregnant women whose pregnancy courses were good with no complications.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2015 2014

All Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] 妊婦のレストレスレッグス症候群(RLS)における周期性下肢運動について2015

    • Author(s)
      坂本遥,畑中愛,山口ゆかり,江藤宏美,近藤英明
    • Organizer
      第31回不眠研究会
    • Place of Presentation
      東京ステーションホテル(東京)
    • Year and Date
      2015-12-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] Restless Legs Syndrome during Pregnancy and Birth Outcome2015

    • Author(s)
      Satoko Araki, Yukari Yamaguchi, Hiromi Eto
    • Organizer
      11th ICM (International Confederation of Midwives) Asia Pacific Regional Conference 2015
    • Place of Presentation
      Pacifico Yokohama, Japan
    • Year and Date
      2015-07-20
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 妊産婦におけるレストレスレッグス症候群の有病率と臨床像2015

    • Author(s)
      近藤英明・江藤宏美
    • Organizer
      日本睡眠学会第40回定期学術集会
    • Place of Presentation
      栃木県総合文化センター(宇都宮)
    • Year and Date
      2015-07-02
    • Related Report
      2015 Annual Research Report
  • [Presentation] 妊娠期におけるレストレスレッグス症候群のスクリーニングと実態2014

    • Author(s)
      畑中愛,山口ゆかり,江藤宏美,近藤英明
    • Organizer
      第30回不眠研究会
    • Place of Presentation
      ステーションコンファレンス東京(東京都千代田区)
    • Year and Date
      2014-12-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Presence of restless leg syndrome and iron deficiency among third trimester of pregnant women in a Japanese urban clinic2014

    • Author(s)
      Yukari Yamaguchi, Hiromi Eto, Yasunori Oka
    • Organizer
      22nd Congress of the European Sleep Research Society
    • Place of Presentation
      Nordea Concert Hall, Solaris Tallinn (Estonia)
    • Year and Date
      2014-09-16 – 2014-09-20
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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