Synthesis of cycloalkenes utilizing unconventional reactivity of magnesium carbenoids
Project/Area Number |
25810030
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Organic chemistry
|
Research Institution | Tokyo University of Science |
Principal Investigator |
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
|
Keywords | マグネシウムカルベノイド / 環化反応 / 求核性 / 求電子性 / カップリング反応 / シクロアルケン / DFT計算 / 計算化学 |
Outline of Final Research Achievements |
Magnesium carbenoids are reactive intermediates in which the magnesium and chlorine atoms are attached to the carbon atom. Magnesium carbenoids can act not only as nucleophiles but also as electrophiles. I developed intramolecular reactions leading to the formation of various cyclic compounds including cycloalkenes utilizing the ambiphilic reactivity of magnesium carbenoids. From the results of DFT calculations of magnesium carbenoids, I found that the molecular geometry of magnesium carbenoids deviated from that of typical organic molecules and that the structural features of magnesium carbenoids contributed to their unconventional reactivity.
|
Report
(4 results)
Research Products
(26 results)