The Relationship of Myeloma cells, Stromal cells and Monocyte under bone marrow microenvironment
| Project/Area Number |
25830120
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Tumor therapeutics
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
IKEDA HIROSHI 札幌医科大学, 道民医療推進学講座, 助教 (60570132)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 多発性骨髄腫 / 単球 / 骨髄腫 / 骨髄微小環境 |
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| Outline of Final Research Achievements |
Multiple myeloma (MM) is a disease characterized by clonal B-cell tumors of slowly proliferating plasma cells within the bone marrow. yeloma cells contacts with bone marrow stromal cells (BMSCs), which secrete factors/cytokines, Our results therefore suggest that the role of monocyte is an important component of the BM microenvironment.
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Report
(4 results)
Research Products
(4 results)
