Relationship between chemical-specific IgGs and childhood allergies
| Project/Area Number |
25860472
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Hygiene and public health
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| Research Institution | University of Occupational and Environmental Health, Japan |
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Principal Investigator |
Tsuji Mayumi 産業医科大学, 医学部, 准教授 (40457601)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 小児 / アレルギー / 化学物質 / 社会医学 / 分子疫学 |
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| Outline of Final Research Achievements |
Study purpose is to analyze the following association for young children.1.the sensitization situation of plastic-resin specific IgG. 2.The relationship between specific IgG antibodies and allergy symptoms.
[Material and Methods] Subjects included 202 children (mean age 19.7 months). A questionnaire survey was answered by a parent, and blood was collected to measure plastic-resin-specific IgGs and mRNA. In addition, adult blood was also collected to measure plastic-resin-specific IgGs (N=104). ［Results］Plastic-resin-specific IgG values were defined as: negative; non-detection (N.D.), positive >0μg;/ml. The ratios of positive groups for AA, BADGE, FA and PPD is following; adult; 15%, 8%, 9%, 18%. young children; 32%, 21%, 14%, 7%. In particular, AA-specific IgG positive levels had a tendency to be detected in asthmatic children.[Conclusion] In young children, there was a trend for some plastic-resin-specific IgGs to be detected in young children more frequently than in adults.
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Report
(5 results)
Research Products
(16 results)
