| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Pancreatic neoplasms such as pancreatic cancer and intraductal papillary mucinous neoplasms are still difficult to diagnose and treat because of insufficient availability of obtaining specimens preoperatively. On the other hand, rapid progress of technical improvements has enabled us to examine genetic abnormalities with a small amount of clinical samples easily.
In this study, we analysed mutational status of pancreatic diseases using clinically obtained pancreatic juice and found that GNAS mutation seen in cases with IPMN is associated with dilation of main pancreatic duct. Though the meanings of this findings need more analysis, we believe our study will contributes to clarify causes of pancreatic disease.
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