Analysis of function on glucose and lipid metabolism of a new secretory factor, Favine, which is highly expressed in vessels and adipose tissue.
| Project/Area Number |
25860767
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Endocrinology
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| Research Institution | Osaka University |
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Principal Investigator |
KOBAYASHI Sachiko 大阪大学, 医学(系)研究科(研究院), 特任研究員 (80649111)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | Favine / 脂肪細胞分化 / 脂肪合成 / 脂質 / 糖尿病 |
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| Outline of Final Research Achievements |
Favine/CCDC3 is a secretory factor, which we identified in 2010. Favine is highly expressed in the aorta and adipose tissue. The Favine mRNA levels are increased in the adipose tissue of obese and diabetic mice than in lean mice. However, its biological function has not yet been elucidated. In this study, we showed that Favine has adipogenic and lipogenic effects. Further investigation on the function of Favine will provide valuable information for revealing underlying mechanisms of metabolic syndrome.
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Report
(4 results)
Research Products
(11 results)
