New approach to relieving pain and distress during high-dose-rate intracavitary irradiation for chervical chancer

• Project/Area Number: 25861073
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Chiba University
• Principal Investigator: Nemoto Miho 千葉大学, 医学(系)研究科(研究院), 講師 (50568665)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
• Keywords: 子宮頸癌 / 腔内照射 / 鎮静 / 安全 / 論文作成 / 情報交換 / 情報収集 / 学会発表 / 症例蓄積

Outline of Final Research Achievements

In order to relieve the pain and distress experienced by women who undergo high-dose rate intracavitary radiotherapy (HDR-ICRT) for cervical cancer and to improve the current status of gynecological brachytherapy in Japan, a new intravenous anesthetic protocol involving the administration of a combination of propofol and ketamine was developed. We have demonstrated that our new intravenous anesthetic protocol produces appropriate fast-acting effects and can be performed by radiation oncologists.

Research Products

• [Journal Article] New approach to relieving pain and distress during high-dose-rate intracavitary irradiation for cervical cancer (2015)
  • Author(s): Miho Watanabe Nemoto, et al.
  • Journal Title: Brachytherapy Volume: 14 Issue: 5 Pages: 642-648
  • DOI: 10.1016/j.brachy.2015.04.009
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Preliminary result of MRI based image guided brachythehrapy in cervical carcinomaa (2016)
  • Author(s): Miho Watanabe Nemoto
  • Organizer: World Congress of Brachytherapy
  • Place of Presentation: Hilton San Francisco Union Square, San Francisco, USA
  • Year and Date: 2016-06-27
  • Int'l Joint Research
• [Presentation] Preliminary result of MRI based image guided brachytehrapy in cervical carcinoa: Chiba University experience (2015)
  • Author(s): Miho Watanabe
  • Organizer: The 28th Annual Meeting of the Japanese Society for Radiation Oncology
  • Place of Presentation: ベイシア文化ホール（群馬県・前橋市）
  • Year and Date: 2015-11-19
• [Presentation] MRI/CT based image guidedbrachytherapyの初期経験 (2015)
  • Author(s): Miho Watanabe
  • Organizer: 日本放射線腫瘍学会小線源治療部会第17回学術大会
  • Place of Presentation: 大宮ソニックシティ（埼玉県・さいたま市・大宮区）
  • Year and Date: 2015-06-26
• [Presentation] Preliminary result of MRI based image guided brachytherapy in cervical carcinoma: Chiba University experience (2015)
  • Author(s): Miho Watanabe Nemoto
  • Organizer: 15th International Congress of Radiation Research
  • Place of Presentation: 国立京都国際会館（京都府・京都市・左京区）
  • Year and Date: 2015-05-25 – 2015-05-29
• [Presentation] Preliminary result of MRI based image guided brachytehrapy in cervical carcinoa: Chiba University experience (2015)
  • Author(s): Miho Watanabe Nemoto
  • Organizer: 15th International Congress of Radiation Research
  • Place of Presentation: 国立京都国際会館（京都府・京都市・左京区）
  • Year and Date: 2015-05-25
  • Int'l Joint Research
• [Presentation] Preliminary result of MRI based image guided brachytherapy in cervical carcinoma: Chiba University experience (2015)
  • Author(s): Miho Watanabe Nemoto
  • Organizer: The 74th Annual Meeting of the Japan Radiological Society
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市・西区）
  • Year and Date: 2015-04-16 – 2015-04-19
• [Presentation] Preliminary result of MRI based image guided brachytehrapy in cervical carcinoa: Chiba University experience (2015)
  • Author(s): Miho Watanabe Nemoto
  • Organizer: 15th International Congress of Radiation Research
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市・西区）
  • Year and Date: 2015-04-16