Development of practical tools for the analysis of multi-dimentional medical MR images

• Project/Area Number: 25861087
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kyoto University
• Principal Investigator: FUJIMOTO Koji 京都大学, 医学(系)研究科(研究院), 助教 (10580110)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
• Keywords: 核磁気共鳴画像 / MRI / ポストプロセシング / 多次元データ / 可視化

Outline of Final Research Achievements

(1) Developed a tool to help drawing VOIs, which are necessary for visualizing results of DTI of the uterus. (2) Developed an interactive GUI for the analysis of kidney ASL data. (3) Developed a script to analyze quantitative parameters obtained from DCE-MRI of patients with uterine cervical cancer. (4) Developed a script to analyze ADC and long term survival of patients with uterine cervical cancer, and showed a presence of correlation. (5) Developed a GUI to estimate arrival time and blood flow of the kidney based on the ASL images, and reported its accuracy.

Research Products

• [Journal Article] Pretreatment Mean Apparent Diffusion Coefficient is Significantly Correlated with Event-free Survival in Patients with FIGO Stages Ib to IIIb Cervical Cancer (2015)
  • Author(s): Himoto Y, Fujimoto K, Kido A, Baba T, Tanaka S, Morisawa N, Koyasu S, Konishi I, Togashi K
  • Journal Title: Int J Gynecol Cancer Volume: -
  • Peer Reviewed
• [Journal Article] Assessment of the Early Predictive Power of Quantitative Magnetic Resonance Imaging Parameters During Neoadjuvant Chemotherapy for Uterine Cervical Cancer. (2014)
  • Author(s): Himoto Y, Fujimoto K, Kido A, Matsumura N, Baba T, Daido S, Kiguchi K, Shitano F, Konishi I, Togashi K.
  • Journal Title: Int J Gynecol Cancer Volume: - Issue: 4 Pages: 751-757
  • DOI: 10.1097/igc.0000000000000124
  • Peer Reviewed
• [Presentation] 3D-SSFP-ASL を用いて腎臓到達時間を考慮した腎血流量計測 (2014)
  • Author(s): 高倉京子、藤本晃司、木戸晶、伏見育崇、岡田知久、坂下尚孝、木村徳典、富樫かおり
  • Organizer: 第 42 回日本磁気共鳴医学会大会
  • Place of Presentation: 京都
  • Year and Date: 2014-09-18 – 2014-09-20
• [Presentation] 3D-SSFP-ASL（ASTAR）を用いた腎血流量計測 (2013)
  • Author(s): 高倉 京子、藤本 晃司、木戸 晶、伏見 育崇、梅岡 成章、岡田 知久、坂下 尚孝、木村 徳典、金澤 裕樹、富樫かおり
  • Organizer: 日本磁気共鳴医学会大会
  • Place of Presentation: 徳島
• [Presentation] プロトン密度強調（PDw）画像を用いない腎血流量定量の試み (2013)
  • Author(s): 高倉 京子、藤本 晃司、木戸 晶、伏見 育崇、梅岡 成章、岡田 知久、坂下 尚孝、木村 徳典、金澤 裕樹、富樫かおり
  • Organizer: 日本磁気共鳴医学会大会
  • Place of Presentation: 徳島