Development of three-dimensional (3D) lung motion assessment on CT

• Project/Area Number: 25861100
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Radiation science
• Research Institution: Kobe University
• Principal Investigator: KOYAMA HISANOBU 神戸大学, 医学部附属病院, 講師 (30546487)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 機能画像 / 呼吸運動 / CT / 呼吸機能 / 慢性閉塞性肺疾患 / 肺癌

Outline of Final Research Achievements

The purpose of this study was to evaluate the utility of three-dimensional (3D) lung motion on inspiratory and expiratory CT for pulmonary functional loss in smoking-related COPD in comparison with morphologically based assessment, such as lung destruction and air trapping assessments. In this study, 3D lung motion parameter assessment was useful for smoking-related COPD assessment in comparison with lung parenchymal destruction and/or air trapping evaluations.

Research Products

• [Journal Article] 3D lung motion assessments on inspiratory/expiratory thin-section CT: Capability for pulmonary functional loss of smoking-related COPD in comparison with lung destruction and air trapping. (2016)
  • Author(s): Koyama H, Ohno Y, Fujisawa Y, Seki S, Negi N, Murakami T, Yoshikawa T, Sugihara N, Nishimura Y, Sugimura K
  • Journal Title: Eur J Radiol Volume: 85(2) Issue: 2 Pages: 352-359
  • DOI: 10.1016/j.ejrad.2015.11.026
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] 3D Lung Motion Assessments on Inspiratory/Expiratory Thin-Section Area-Detector CT (ADCT): Capability for Pulmonary Functional Loss and Clinical Stage Evaluation of Smoking-Related COPD in Comparison with Lung Destruction and Air Trapping (2015)
  • Author(s): Hisanobu Koyama, Yoshiharu Ohno, Yasuko Fujisawa, Shinichiro Seki, Takeshi Yoshikawa, Sumiaki Matsumoto, Noriyuki Negi, Tohru Murakami, Naoki Sugihara, Hitoshi Yamagata, Kazuro Sugimura
  • Organizer: RSNA 2015
  • Place of Presentation: アメリカ シカゴ
  • Year and Date: 2015-11-29
  • Int'l Joint Research
• [Presentation] 3D Motion Analysis on Inspiratory and Expiratory CT: Utility for Determining the Influence of Lung Motion to Postoperative Lung Function in 101 Oncologic Patients receiving Lobectomy (2015)
  • Author(s): Hisanobu Koyama, Yoshiharu Ohno, Yasuko Fujisawa, Shinichiro Seki, Sumiaki Matsumoto, Naoki Sugihara, Takeshi Yoshikawa, Hitoshi Yamagata, Kazuro Sugimura
  • Organizer: European Congress of Radiology 2015
  • Place of Presentation: ウィーン、オーストリア
  • Year and Date: 2015-03-04 – 2015-03-08
• [Presentation] 3D Lung Motion and Destruction Assessments from Inspiratory and Expiratory Thin-Section MDCT: Utility for Pulmonary Functional Loss and Clinical Stage Evaluation in Smokers (2014)
  • Author(s): Hisanobu Koyama, Yoshiharu Ohno, Yasuko Fujisawa, Shinichiro Seki, Mizuho Nishio, Sumiaki Matsumoto, Naoki Sugihara, Hitoshi Yamagata, Kazuro Sugimura
  • Organizer: The 73rd Annual Meeting of the Japan Radiological Society
  • Place of Presentation: 横浜
  • Year and Date: 2014-04-10 – 2014-04-13
• [Presentation] COPDにおける吸気呼気CTを用いた3次元的呼吸運動解析 (2014)
  • Author(s): 神山久信、大野良治、藤澤恭子、関紳一郎、西尾瑞穂、松本純明、杉原直樹、山形 仁、杉村和朗
  • Organizer: 第6回 呼吸機能イメージング研究会学術集会
  • Place of Presentation: 札幌
• [Presentation] 3D Lung Motion and Destruction Assessments from Inspiratory and Expiratory Thin-Section MDCT: Utility for Pulmonary Functional Loss and Clinical Stage Evaluation in Smokers (2013)
  • Author(s): Hisanobu Koyama, Yoshiharu Ohno, Yasuko Fujisawa, Shinichiro Seki, Mizuho Nishio, Takeshi Yoshikawa, Sumiaki Matsumoto, Naoki Sugihara, Kazuro Sugimura, Hitoshi Yamagata
  • Organizer: Radiological Society of North America 2014
  • Place of Presentation: Chicago, USA