A study of biological effect of photonuclear reactions with high-energy X-ray radiation therapy
| Project/Area Number |
25861144
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | National Cancer Center Japan |
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Principal Investigator |
Wakita Akihisa 国立研究開発法人国立がん研究センター, 中央病院, 医学物理士 (30595731)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 放射線物理 / 放射線生物 / MKM / CR-39 / 放射線治療 / X線 / 光核反応 / RBE / X線治療 |
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| Outline of Final Research Achievements |
I have derived the relative biological effectiveness (RBE) of the combined field with high-energy photons and secondary particles caused from photonuclear reactions.
In this study, I was used both experimental data obtained by solid state track detector and biological model called “Microdosimetric Kinetic Model (MKM)” to calculate RBE. Radiation quality can change with the measurement depth because the ratio of the fluence of photons and secondary particles can change, thus I was calculated RBE for the depth of the surface, 5 cm and 10 cm in the water-equivalent phantom. RBE of the combined field was 1.01 for all depths.
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Report
(5 results)
Research Products
(4 results)
