• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

A study of biological effect of photonuclear reactions with high-energy X-ray radiation therapy

Research Project

Project/Area Number 25861144
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionNational Cancer Center Japan

Principal Investigator

Wakita Akihisa  国立研究開発法人国立がん研究センター, 中央病院, 医学物理士 (30595731)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords放射線物理 / 放射線生物 / MKM / CR-39 / 放射線治療 / X線 / 光核反応 / RBE / X線治療
Outline of Final Research Achievements

I have derived the relative biological effectiveness (RBE) of the combined field with high-energy photons and secondary particles caused from photonuclear reactions.
In this study, I was used both experimental data obtained by solid state track detector and biological model called “Microdosimetric Kinetic Model (MKM)” to calculate RBE. Radiation quality can change with the measurement depth because the ratio of the fluence of photons and secondary particles can change, thus I was calculated RBE for the depth of the surface, 5 cm and 10 cm in the water-equivalent phantom. RBE of the combined field was 1.01 for all depths.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2014 2013

All Journal Article (1 results) Presentation (3 results)

  • [Journal Article] A study on the influence of photonuclear reactions on the radiation quality of therapeutic high energy X-ray beam2014

    • Author(s)
      Akihisa Wakita
    • Journal Title

      Japanese Jounal of Medical Physics

      Volume: 34 Pages: 198-198

    • Related Report
      2013 Research-status Report
  • [Presentation] A Study on the Influence of Photonuclear Reactions on the Biological Effectiveness of Therapeutic High Energy X-ray Beam2014

    • Author(s)
      Akihisa Wakita
    • Organizer
      American Association of Physicist in Medicine 56th annual meeting
    • Place of Presentation
      Austin, USA
    • Year and Date
      2014-07-20 – 2014-07-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 高エネルギーX線治療における光核反応粒子の線質に関する検討2014

    • Author(s)
      脇田 明尚
    • Organizer
      第107回日本医学物理学会
    • Place of Presentation
      横浜
    • Related Report
      2013 Research-status Report
  • [Presentation] A STUDY OF LET DISTRIBUTION OF PHOTONUCLEAR REACTIONS IN HIGH ENERGY X-RAY THERAPY2013

    • Author(s)
      Akihisa Wakita
    • Organizer
      12th SYMPOSIUM ON NEUTRON AND ION DOSIMETRY
    • Place of Presentation
      フランス
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi