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Sentinel lymph node laparoscopic biopsy for endometrial cancer using indocyanine green near-infrared fluorescence imaging

Research Project

Project/Area Number 25861492
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Obstetrics and gynecology
Research InstitutionOsaka University

Principal Investigator

KOBAYASHI Eiji  大阪大学, 医学(系)研究科(研究院), 助教 (50614773)

Project Period (FY) 2013-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords婦人科腫瘍
Outline of Final Research Achievements

【Objectives】To compare the detection rate of sentinel lymph nodes (SLNs) between indocyanine green(ICG) method and colorimetric method for uterine cancer during laparoscopic surgery. 【Methods】 From 5/2012, We performed 17 cases of laparoscopic Near Infrared NIR fluorescence imaging SLN biopsy. Diluted ICG was injected into the uterine cervix before the surgery. Blue dye was concurrently injected in some cases.【Results】 We used ICG in 17 cases and blue dye was used concurrently in 15 cases. We could identify SLN with bilateral pelvic mapping in 70.5% of the cases using ICG. Looking at the blue dye group, we could identify SLN with bilateral pelvic mapping in 20%. In bilateral SLN biopsy, ICG was significantly superior to blue dye method.【Conclusion】Even though these cases were conducted during the early learning curve stage to perform the procedure, we found laparoscopic NIR fluorescence imaging for SLN to be superior to the blue dye method with low complications.

Report

(3 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2014 2013 Other

All Presentation (5 results)

  • [Presentation] Sentinel lymph node laparoscopic biopsy for uterine and cervical malignancies using indocyanine green near-infrared fluorescence imaging2014

    • Author(s)
      Kobayashi, E.
    • Organizer
      23rd Annual Congress ESGE
    • Place of Presentation
      Brussels, Belgium
    • Year and Date
      2014-09-24 – 2014-09-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] ICG(インドシアニングリーン)蛍光イメージングによる腹腔鏡下センチネルリンパ生検2014

    • Author(s)
      小林栄仁 角田守 森本晶子 高田友美 松崎慎哉 橋本香映 木村敏啓 磯部晶 馬淵誠士 上田豊 澤田健二郎 吉野潔 藤田征巳 木村正
    • Organizer
      第54回日本産科婦人科内視鏡学会学術講演会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] An internal retractor for the management of the vesicouterine ligament during laparoscopic radical hysterectomy2013

    • Author(s)
      Kobayashi, E.
    • Organizer
      22nd Annual Congress European Society of Gynaecological Endoscopy
    • Place of Presentation
      Berlin, Germany
    • Related Report
      2013 Research-status Report
  • [Presentation] ICG(インドシアニングリーン)蛍光イメージングの腹腔鏡下センチネルリンパ節生検への応用2013

    • Author(s)
      小林栄仁
    • Organizer
      第53回日本産科婦人科内視鏡学会学術講演会
    • Place of Presentation
      愛知
    • Related Report
      2013 Research-status Report
  • [Presentation] 内視鏡手術症例の少ない施設で安全に手術を導入するための取り組み

    • Author(s)
      小林栄仁 細井文子 木村敏啓 上田豊 吉野潔 藤田征巳 筒井建紀 木村正
    • Organizer
      第135回東北連合産科婦人科学会総会・学術講演会
    • Place of Presentation
      山形
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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