Experiment on new material composed of Tenascin-C coated collagen sponge for direct pulp capping
Project/Area Number |
25861811
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Conservative dentistry
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Research Institution | Tokyo Dental College |
Principal Investigator |
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Project Period (FY) |
2013-04-01 – 2015-03-31
|
Project Status |
Completed (Fiscal Year 2014)
|
Budget Amount *help |
¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
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Keywords | 歯髄 / 直接覆罩法 / 細胞外マトリックス / Tenascin-C / 第三象牙質 / 覆罩法 / Collagen sponge / 歯髄覆罩材 / 機能性マトリックス |
Outline of Final Research Achievements |
It is important that dental pulp tissue preserved for direct pulp capping. We research that new material composed mainly of extracellular matrix has a biocompatibility for direct pulp capping. This experiment aimed at analysis that rat dental pulp cells promote to produce tertiary dentin used Tenascin-C (TN-C) coated collagen sponge implanted at defect dentin area for direct pulp capping. Present results showed that dental pulp tissue around TN-C coated collagen sponge increased calcification after 1month in vivo. These finding suggest that TN-C coated sponge may be useful for new material of direct pulp capping.
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Report
(3 results)
Research Products
(1 results)