| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Outline of Final Research Achievements |
This study aimed to propose new treatment methodology for lymph node metastasis in oral squamous cell carcinoma(OSCC). Especially we focused on Tumor associated macrophage (M2 macrophage) in the tumor microenvironment in OSCC.Our data showed that M2 macrophage strong expression group was significantly related to locally progressive, lymph node metastasis, and prognosis. Moreover, this group showed the tendency that highly expression rate in COX-2 and VEGF-C. In conclusion M2 macrophage in the tumor microenvironment in OSCC might be become the treatment target for prevent the locally progressive, lymph node metastasis.
|
