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Development of innovative biosensors using phonon transport in nanostructures

Research Project

Project/Area Number 26286035
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Nano/Microsystems
Research InstitutionOsaka University

Principal Investigator

Hirao Masahiko  大阪大学, 基礎工学研究科, 教授 (80112027)

Co-Investigator(Kenkyū-buntansha) 草部 浩一  大阪大学, 基礎工学研究科, 准教授 (10262164)
中村 暢伴  大阪大学, 基礎工学研究科, 助教 (50452404)
荻 博次  大阪大学, 基礎工学研究科, 准教授 (90252626)
小野 輝男  京都大学, 化学研究所, 教授 (90296749)
Co-Investigator(Renkei-kenkyūsha) ONO Teruo  京都大学, 化学研究所, 教授 (90296749)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Keywordsフォノン / バイオセンサー / フェムト秒レーザー / ナノ構造体 / 多チャンネル / 計測工学 / ナノメカニックス / ナノマイクロデバイス
Outline of Final Research Achievements

We succeeded in developing the measurement system for monitoring the phonon-transport process in nanostructures, such as ultra-thin films, nanowires, and nanoplates, using the pump-probe technique with the femtosecond pulse lasers. We then incorporated this system into a microscopic system for achieving the phonon measurements at a localized region. We further applied this system as a multichannel biosensor for monitoring antigen-antibody binding reactions.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (12 results)

All 2016 2015 2014

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (10 results) (of which Int'l Joint Research: 4 results,  Invited: 4 results)

  • [Journal Article] Impact of interface stiffness in surface-wave resonances on nano-strip-attached substrates2016

    • Author(s)
      H. Ogi, S. Masuda, A. Nagakubo, N. Nakamura, M. Hirao, K. Kondou, and T. Ono
    • Journal Title

      Physical Review B

      Volume: 93 Issue: 2 Pages: 024112-024112

    • DOI

      10.1103/physrevb.93.024112

    • NAID

      120007145746

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Formation of continuous metallic film on quartz studied by noncontact resonant ultrasound spectroscopy2015

    • Author(s)
      N. Nakamura, N. Yoshimura, H. Ogi, and M. Hirao
    • Journal Title

      Journal of Applied Physics

      Volume: 118 Issue: 8 Pages: 085302-085302

    • DOI

      10.1063/1.4928959

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Presentation] Elastic properties of piezoelectric crystals2016

    • Author(s)
      荻博次
    • Organizer
      International Symposium of Ferroelectric Materials Toward Energy Harvesting
    • Place of Presentation
      Ryukoku University Avanti Kyoto Hall, Kyoto
    • Year and Date
      2016-02-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Thin-Film Elastic Constants and Their Temperature Behaviors Studied by Picosecond Ultrasound Spectroscopy2015

    • Author(s)
      荻博次
    • Organizer
      6th International Symposium on Acoustic Wave Devices for Future Mobile Communication Systems
    • Place of Presentation
      Keyaki Hall, Chiba University
    • Year and Date
      2015-11-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Guided wave propagation in a 2-D patterned nano-bridge studied by picosecond ultrasonics2015

    • Author(s)
      長久保白、岩上慈、荻博次、谷口卓也、小野輝男、平尾雅彦
    • Organizer
      第36回超音波エレクトロニクスの基礎と応用に関するシンポジウム
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2015-11-06
    • Related Report
      2015 Annual Research Report
  • [Presentation] タンパク質を介するフォノン輸送を利用したマイクロドット大規模多チャンネルバイオセンサー2015

    • Author(s)
      岩上 慈, 荻 博次, 長久保 白, 平尾 雅彦, 谷口 卓也, 小野 輝男
    • Organizer
      日本機械学会 熱工学カンファレンス2015
    • Place of Presentation
      大阪大学コンベンションセンター
    • Year and Date
      2015-10-25
    • Related Report
      2015 Annual Research Report
  • [Presentation] Surface-wave resonance on substrates with copper nanowires2015

    • Author(s)
      Hirotsugu Ogi, Shoichi Masuda, Akira Nagakubo, Masahiko Hirao
    • Organizer
      IEEE International Ultrasonic Symposium 2015
    • Place of Presentation
      Taipei International Convention Center
    • Year and Date
      2015-10-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] タンパク質を横切るフォノン輸送を利用したマイクロドット大規模多チャンネルバイオセンサー2015

    • Author(s)
      岩上慈、荻博次、長久保白、平尾雅彦、谷口卓也、小野輝男
    • Organizer
      第76回応用物理学会秋季学術講演会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-09-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] Ultrafast Heat Transport Across Protein Layer: The Microdot Biosensor Array2015

    • Author(s)
      荻博次、岩上慈、石田秀士、長久保白、平尾雅彦
    • Organizer
      The 15th International Conference on Phonon Scattering in Condensed Matter
    • Place of Presentation
      University of Nottingham, Nottingham, United Kingdom
    • Year and Date
      2015-07-12
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 音響バイオセンサーの最前線2014

    • Author(s)
      荻 博次
    • Organizer
      化学とマイクロ・ナノシステム学会第30回研究会 (CHEMINAS 30)
    • Place of Presentation
      北海道大学札幌キャンパス
    • Year and Date
      2014-10-03
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] ピコ秒フォノン計測によるマイクロドットを用いた大規模多チャンネルバイオセンサーの開発2014

    • Author(s)
      岩上慈,荻博次,長久保白,中村暢伴,平尾雅彦,平松亮,小野輝男
    • Organizer
      第75回応用物理学会秋季学術講演会
    • Place of Presentation
      北海道大学札幌キャンパス
    • Year and Date
      2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 極短光を用いた超高周波力学共振スペクトロスコピー:ナノ材料の弾性定数計測および超高感度バイオセンサーへの応用2014

    • Author(s)
      荻 博次
    • Organizer
      第53回光波センシング技術研究会講演会「光パルス技術と光波センシング」
    • Place of Presentation
      東京理科大学 森戸記念館
    • Year and Date
      2014-06-19
    • Related Report
      2014 Annual Research Report
    • Invited

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Published: 2014-04-04   Modified: 2018-03-22  

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