Development of energy monito for cerebral cortex using NADH fluorescence
Project/Area Number |
26293345
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Anesthesiology
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Research Institution | Okayama University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
山根 延元 岡山大学, 自然科学研究科, 准教授 (80174762)
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Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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Keywords | 脳虚血 / ミトコンドリア / モニター / NADH / エネルギー状態 / モニタ- |
Outline of Final Research Achievements |
To visualize the changes in NADH fluorescence, the signal intensities of NADH fluorescence were divided by those in a control image and were shown in 256-gradation gray scale. Therefore, any movements in the camera and the subjects strongly diminish the quality of the image. In the present study, we used image matching method. This method replaces the original image to the image showing a local feature and executes the pattern matching with use of statistical technique.
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Report
(4 results)
Research Products
(4 results)
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[Journal Article] NADH fluorescence imaging and the histological impact of cortical spreading depolarization during the acute phase of subarachnoid hemorrhage in rats.2017
Author(s)
Shimizu T, Hishikawa T, Nishihiro S, Shinji Y, Takasugi Y, Haruma J, Hiramatsu M, Kawase H, Sato S, Mizoue R, Takeda Y, Sugiu K, Morimatsu H, Date I
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Journal Title
J Neurosurg
Volume: 27
Pages: 1-7
Related Report
Peer Reviewed
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