Phase II cardiac rehabilitation in patients with heart failure due to cardiovascular diseases
| Project/Area Number |
26350585
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Kitasato University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
小倉 彩 北里大学, 医療衛生学部, 助教 (10337991)
野田 千春 北里大学, 医学部, 助教 (80365080)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 心筋重量 / 下肢筋力 / 運動時血圧上昇 / 高血圧症 / 運動負荷試験 / 自律神経活動 / リハビリテーション / 心肥大 / 生活習慣病 / 血圧上昇 / 酸化ストレス / 耐糖能異常 / 左室肥大 / 心臓リハビリテーション / 高齢者 / 心不全 |
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| Outline of Final Research Achievements |
This study aimed to investigate relationships between muscle weakness, blood pressure (BP) elevation during exercise and left ventricular mass (LVM) in patients with hypertension. Eighty-six hypertensive patients aged 69 ± 8 years with controlled resting BP (i.e., <140/90 mmHg) were recruited. Left ventricular mass index (LVM) and knee extension muscle strength were measured. Difference between baseline and peak systolic BP during the ergometer exercise test was defined as BP elevation during exercise (ΔSBP). Muscle strength was negatively correlated with ΔSBP (r=-0.230, P=0.033) and LVMI (r=-0.233, P=0.031). LVMI was positively correlated with ΔSBP (r=0.307, P=0.033). Muscle strength was a significant independent factor associated with LVMI (β=-0.319, P=0.012). Our findings suggest that muscle weakness is associated with an increase of LVM through excessive BP elevation during exercise in patients with hypertension.
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Report
(4 results)
Research Products
(26 results)
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[Journal Article] Muscle Weakness is Associated with an Increase of Left Ventricular Mass through Excessive Blood Pressure Elevation during Exercise in Patients with Hypertension2017
Author(s)
Yumi KAMADA, Takashi MASUDA, Shinya TANAKA, Daisuke KAMEKAWA, Ayako AKIYAMA, Takeshi NAKAMURA, Kanae YABU, Nobuaki HAMAZAKI, Michihito OKUBO, Naoyuki KOBAYASHI, Junya AKO
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Journal Title
International Heart Journal
Volume: 印刷中
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Utility of SARC-F for Assessing Physical Function in Elderly Patients With Cardiovascular Disease2017
Author(s)
Shinya Tanaka, Kentaro Kamiya, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Takashi Masuda, Junya Ako
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Journal Title
Journal of the American Medical Directors Association
Volume: 18
Pages: 176-181
Related Report
Peer Reviewed
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[Journal Article] Prognostic Usefulness of Arm but not Calf Circumference in Patients ＞65 Years of Age with Cardiovascular Disease2017
Author(s)
Kentaro Kamiya, Takashi Masuda, Yuya Matsue, Nobuaki Hamazaki, Ryota Matsuzawa, Shinya Tanaka, Kohei Nozaki, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Junya Ako
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Journal Title
American Journal of Cardiology
Volume: 119
Pages: 186-191
Related Report
Peer Reviewed
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[Journal Article] Stretching Exercises Improve Vascular Endothelial Dysfunction through Oxidative Stress Attenuation in Chronic Heart Failure Patients with an Implantable Cardioverter Defibrillator2017
Author(s)
Michitaka Kato, Takashi Masuda, Michio Ogano, Kazuki Hotta, Hisato Takagi, Shinya Tanaka, Yumi Kamada, Ayako Akiyama, Daisuke Kamekawa, Ryosuke Shimizu, Minoru Tabata, Jun Tanabe, Takuya Umemoto
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Journal Title
Journal of Cardiopulmonary Rehabilitation and Prevention
Volume: 37
Pages: 130-138
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Low ankle brachial index is associated with the magnitude of impaired walking endurance in patients with heart failure2016
Author(s)
Shinya Tanaka, Kentaro Kamiya, Takashi Masuda, Nobuaki Hamazaki, Ryota Matsuzawa, Kohei Nozaki, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Junya Ako
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Journal Title
International Journal of Cardiology
Volume: 224
Pages: 400-405
Related Report
Peer Reviewed
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[Journal Article] Complementary role of arm circumference to body mass index in risk stratification in heart failure2016
Author(s)
Kentaro Kamiya, Takashi Masuda, Yuya Matsue, Takayuki Inomata, Nobuaki Hamazaki, Ryota Matsuzawa, Shinya Tanaka, Kohei Nozaki, Emi Maekawa, Chiharu Noda, Minako Yamaoka-Tojo, Atsuhiko Matsunaga, Tohru Izumi, Junya Ako
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Journal Title
J Am Coll Cardiol Heart Failure
Volume: 4
Pages: 265-273
Related Report
Peer Reviewed
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[Journal Article] Low-intensity resistance training with blood flow restriction improves vascular endothelial function and peripheral blood circulation in healthy elderly people2016
Author(s)
Ryosuke Shimizu, Kazuki Hotta, Shuhei Yamamoto, Takuya Matsumoto, Kentaro Kamiya, Michitaka Kato, Nobuaki Hamazaki, Daisuke Kamekawa, Ayako Akiyama, Yumi Kamada, Shinya Tanaka, Takashi Masuda
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Journal Title
Eur J Appl Physiol
Volume: 116
Pages: 749-757
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Safety of neuromuscular electrical stimulation in patients implanted with cardioverter defibrillators2016
Author(s)
Kentaro Kamiya, Akira Satoh, Shinichi Niwano, Shinya Tanaka, Kazumasa Miida, Nobuaki Hamazaki, Emi Maekawa, Ryota Matsuzawa, Kohei Nozaki, Takashi Masuda, Junya Ako
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Journal Title
Journal of Electrocardiology
Volume: 49
Pages: 99-101
Related Report
Peer Reviewed
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