Role of mirror neuron system for social learning in common marmosets

• Project/Area Number: 26430031
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Neurophysiology / General neuroscience
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: Suzuki Wataru 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 微細構造研究部, 室長 (80332336)
• Co-Investigator(Renkei-kenkyūsha): Ichinohe Noritaka 神経研究所, 微細構造研究部, 部長 (00250598) ; Miyakawa Naohisa 神経研究所, 微細構造研究部, 研究員 (60415312) ; Banno Taku 神経研究所, 微細構造研究部, 研究員 (70598440) ; Abe Hiroshi 神経研究所, 微細構造研究部, 研究員 (10711161)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: バイオロジカルモーション / 上側頭溝 / マーモセット / 生体内神経結合イメージング

Outline of Final Research Achievements

Using intrinsic optical signal imaging, the area representing the others' action, food grasping behavior, are visualized in the superior temporal sulcus of common marmoset. The responses in this area decrease when grasping behavior without the food is presented, indicating that the area also codes for the aim of the other. To investigate the input source of the aim of the other, ibotenic acid are injected in the frontal lobe including the orbitofrontal cortex and the unit recording in the superior temporal sulcus are conducted. After the injection, the response of some units to the others' action significantly decrease. To quantitatively examine the marmoset behavior, I develop an algorithm to extract motion information from animal movie to quantitatively. Using these various experimental methods, the mechanism of the mirror neuron system will be elucidated.

Research Products

• [Journal Article] Sound frequency representation in the auditory cortex of the common marmoset visualized using optical intrinsic signal imaging. (2018)
  • Author(s): Tani T, Abe H, Hayami T, Banno T, Miyakawa N, Kitamura N, Mashiko H, Ichinohe N, Suzuki W
  • Journal Title: eNeuro Volume: 5 Issue: 2 Pages: 1-13
  • DOI: 10.1523/eneuro.0078-18.2018
  • Peer Reviewed / Open Access
• [Journal Article] 3D reconstruction of brain section images for creating axonal projection maps in marmosets. (2017)
  • Author(s): Abe H, Tani T, Mashiko H, Kitamura N, Miyakawa N, Mimura K, Sakai K, Suzuki W, Kurotani T, Mizukami H, Watakabe A, Yamamori T, Ichinohe N.
  • Journal Title: J Neurosci Methods Volume: 286 Pages: 102-113
  • DOI: 10.1016/j.jneumeth.2017.04.016
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Novel method of extracting motion from natural movies (2017)
  • Author(s): Suzuki Wataru、Ichinohe Noritaka、Tani Toshiki、Hayami Taku、Miyakawa Naohisa、Watanabe Satoshi、Takeichi Hiroshige
  • Journal Title: Journal of Neuroscience Methods Volume: 291 Pages: 51-60
  • DOI: 10.1016/j.jneumeth.2017.08.006
  • Peer Reviewed / Open Access
• [Journal Article] Representation of glossy material surface in ventral superior temporal sulcal area of common marmosets (2017)
  • Author(s): Miyakawa N, Banno T, Abe H, Tani T, Suzuki W, Ichinohe N
  • Journal Title: Frontiers in neural circuits Volume: 11 Pages: 17-17
  • Peer Reviewed / Open Access
• [Journal Article] Functional columns in superior temporal sulcus areas of the common marmoset. (2015)
  • Author(s): Suzuki W, Tani T, Banno T, Miyakawa N, Abe H, Ichinohe N
  • Journal Title: Neuroreport Volume: 26 Issue: 18 Pages: 1133-1139
  • DOI: 10.1097/wnr.0000000000000483
  • Peer Reviewed / Open Access
• [Journal Article] Mirror neurons in a New World monkey, common marmoset (2015)
  • Author(s): Suzuki W, Banno T, Miyakawa N, Abe H, Goda N, Ichinohe N
  • Journal Title: Frontiers in Neuroscience 9 459 Volume: ９ Pages: 459-459
  • DOI: 10.3389/fnins.2015.00459
  • Peer Reviewed / Open Access
• [Presentation] Marmoset as a model for human speech perception and its disorder． (2017)
  • Author(s): T. Banno, W. Suzuki, N. Miyakawa, T. Tani, N. Ichinohe
  • Organizer: 第7回日本マーモセット研究会大会
• [Presentation] げっ歯類とサルのためのオープンソース３次元ビデオ行動解析システムの開発と神経科学への応用 (2017)
  • Author(s): 松本淳平, 西丸広史, 高村雄策, 三村喬生, 浅場明莉, 鈴木航, 一戸紀孝, 南本敬史, 小野武年, 西条寿夫
  • Organizer: 2017年度生命科学系学会合同年次大会
• [Presentation] 3D-Tracker, an open-source 3D video based behavioral analysis system for laboratory animals for neuroscience (2017)
  • Author(s): J. Matsumoto, H. Nishimaru, Y. Takamura, K. Mimura, A. Asaba, W. Suzuki, N. Ichinohe, T. Minamimoto, T. Ono, H. Nishijo
  • Organizer: Society for Neuroscience
  • Int'l Joint Research
• [Presentation] Axonal projection map of auditory areas in the common marmoset (2017)
  • Author(s): H. Abe, T. Tani, H. Mashiko, N. Kitamura, K. Sakai, T. Hayami, N. Miyakawa, W. Suzuki, H. Mizukami, A. Watakabe, T. Yamamori, N. Ichinohe
  • Organizer: Society for Neuroscience
  • Int'l Joint Research
• [Presentation] Temporal and rate coding of sound envelope and temporal fine structures of vocalizations in the primary auditory cortex of marmoset monkeys (2017)
  • Author(s): T. Banno, W. Suzuki, N. Miyakawa, T. Tani, N. Ichinohe
  • Organizer: Society for Neuroscience
• [Presentation] Function of amplitude and frequency modulations underlying vocal processing in the primary auditory cortex of common marmosets (2017)
  • Author(s): T. Hayami, W. Suzuki, T. Banno, N. Miyakawa, T. Tani, S. Watanabe, N. Ichinohe
  • Organizer: 第40回日本神経科学大会
• [Presentation] Axonal projection map of auditory areas in the common marmoset (2017)
  • Author(s): H. Abe, T. Tani, H. Mashiko, N. Kitamura, K. Sakai, T. Hayami, N. Miyakawa, W. Suzuki, H. Mizukami, A. Watakabe, T. Yamamori, N. Ichinohe
  • Organizer: 第40回日本神経科学大会
• [Presentation] Functional organization of the auditory parabelt in the common marmoset in respect to representation of the sound frequencies (2017)
  • Author(s): T. Tani, W. Suzuki, T. Hayami, T. Banno, N. Miyakawa, S. Watanabe, H. Abe, N. Ichinohe
  • Organizer: 第40回日本神経科学大会
• [Presentation] In vivo visualization of multiple areas around the superior temporal sulcus of the common marmoset. (2016)
  • Author(s): W. SUZUKI, T. TANI, T. BANNO, N. MIYAKAWA, H. ABE, T. HAYAMI, N. ICHINOHE
  • Organizer: SFN
  • Place of Presentation: サンディエゴ
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Slow rhythms in conspecific vocalisations are over-represented in the primary auditory cortex of common marmosets. (2016)
  • Author(s): T. BANNO, W. SUZUKI, N. MIYAKAWA, T. TANI, N. ICHINOHE
  • Organizer: SFN
  • Place of Presentation: サンディエゴ
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Representation of glossy material surfaces in common marmoset temporal visual cortex． (2016)
  • Author(s): N. MIYAKAWA, T. BANNO, H. ABE, T. TANI, W. SUZUKI, N. ICHINOHE
  • Organizer: SFN
  • Place of Presentation: サンディエゴ
  • Year and Date: 2016-11-12
  • Int'l Joint Research
• [Presentation] Slow periodic modulations in conspecific vocalizations are over-represented in the primary auditory cortex of common marmosets． (2016)
  • Author(s): Taku Banno, Wataru Suzuki, Naohisa Miyakawa, Toshiki Tani, Noritaka Ichinohe
  • Organizer: 日本神経科学大会
  • Place of Presentation: 横浜
  • Year and Date: 2016-07-20
• [Presentation] Visualization of functional areas in superior temporal sulcus of common marmoset revealed by optical intrinsic signal imaging (2015)
  • Author(s): Wataru Suzuki, Toshiki Tani, Naohisa Miyakawa, Taku Banno, Hiroshi Abe, Noritaka Ichinohe
  • Organizer: 第38回 日本神経科学大会
  • Place of Presentation: 神戸 神戸国際会議場
  • Year and Date: 2015-07-28
• [Presentation] Tonotopic organizations in the auditory cortex in the common marmoset (2015)
  • Author(s): Toshiki Tani, Wataru Suzuki, Taku Banno, Naohisa Miyakawa, Hiroshi Abe, Noritaka Ichinohe
  • Organizer: 第38回 日本神経科学大会
  • Place of Presentation: 神戸 神戸国際会議場
  • Year and Date: 2015-07-28
• [Presentation] Methods for reconstructing 3D brain data from histological sections for making axonal projection maps in the marmoset (2015)
  • Author(s): Hiroshi Abe, Toshiki Tani, Hiromi Mashiko, Naohisa Miyakawa, Koki Mimura, Kazuhisa Sakai, Wataru Suzuki, Tohru Kurotani, Noritaka Ichinohe
  • Organizer: 第38回 日本神経科学大会
  • Place of Presentation: 神戸 神戸国際会議場
  • Year and Date: 2015-07-28
• [Presentation] Gloss representation in multiple areas of common marmoset temporal visual cortex (2015)
  • Author(s): Naohisa Miyakawa, Taku Banno, Hiroshi Abe, Toshiki Tani, Wataru Suzuki, Noritaka Ichinohe
  • Organizer: 第38回 日本神経科学大会
  • Place of Presentation: 神戸 神戸国際会議場
  • Year and Date: 2015-07-28
• [Presentation] Neuronal mechanisms of vocalization sound processing in the primary auditory area of common marmosets (2014)
  • Author(s): Banno T, Suzuki W, Miyakawa N, Abe H, Ichinohe N
  • Organizer: Society for Neuroscience
  • Place of Presentation: Walter E. Washington Convention Center, Washington DC
  • Year and Date: 2014-11-16
• [Presentation] 内因性光計測法を用いたコモンマーモセット聴覚野におけるトノトピーイメージング (2014)
  • Author(s): 鈴木航, 宮川尚久, 坂野拓, 阿部央, 一戸紀孝
  • Organizer: 第37回日本神経科学大会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2014-09-13
• [Presentation] Shitsukan coding in marmoset visual neural network including posterior superior temporal area (2014)
  • Author(s): Miyakawa N, Banno T, Abe H, Suzuki W, Ichinohe N
  • Organizer: 第37回日本神経科学大会
  • Place of Presentation: パシフィコ横浜、横浜
  • Year and Date: 2014-09-13
• [Book] 臨床眼科 増刊号 (2014)
  • Author(s): 鈴木航, 角田和繁, 谷藤学
  • Publisher: 医学書院