Elucidation of insecticidal activity mechanism of B. thuringiensis Cry44Aa toxin
| Project/Area Number |
26450463
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Insect science
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | entomocidus INA288 / Cry44Aaトキシン / B. thuringiensis / トキシンレセプター / アルカリフォスファターゼ / ABCトランスポーター / ネッタイシマカ / Cry44Aa toxin / INA288 / Aedes aegypti / Culex spp. / israelensis / receptor / Cry44Aa / アミノペプチターゼＮ / ＡＴＰ結合カセットトランスポーター / レセプター / バキュロウイルス / イエカ / シマカ / 殺虫剤抵抗性 |
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| Outline of Final Research Achievements |
I have been conducting research aiming at elucidating the insecticidal activity mechanism of Cry44Aa toxin produced by Bacillus thuringiensis entomocidus INA 288, which is known to have highly insecticidal activity against Aedes aegypti and Culex pippins which intermediate tropical infectious diseases. As a result of research for Cry44Aa toxin receptor molecules in A. aegypti which play an important role in insecticidal activity mechanism, alkaline phosphatase and ABC transferase were identified as candidate molecules.
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Report
(4 results)
Research Products
(16 results)
